Biological monitoring in occupational exposure to low levels of 1,3-butadiene

S. Fustinoni; L. Perbellini; L. Soleo; M. Manno; V. Foà

doi:10.1016/j.toxlet.2003.12.046

Biological monitoring in occupational exposure to low levels of 1,3-butadiene

S. Fustinoni, L. Perbellini, L. Soleo, M. Manno, V. Foà

Fondazione IRCCS Ca' Granda- Ospedale Maggiore Policlinico

Research output: Contribution to journal › Article › peer-review

Abstract

Exposure to 1,3-butadiene (BD), a probable carcinogen to humans, was investigated in two groups of subjects working in a petrochemical plant where BD is produced and used to prepare polymers: 42 occupationally exposed workers and 43 internal non-occupationally exposed controls. BD personal exposure was very low but significantly different in the two groups (median airborne BD 1.5 and 0.4μg/m³ in exposed and controls, respectively). Similarly, BD in blood and urine, but not in exhaled air, was higher in the exposed workers than in controls (blood BD 3.7ng/l versus

Original language	English
Pages (from-to)	353-360
Number of pages	8
Journal	Toxicology Letters
Volume	149
Issue number	1-3
DOIs	https://doi.org/10.1016/j.toxlet.2003.12.046
Publication status	Published - Apr 1 2004

Keywords

1,3-Butadiene
Biomarkers
Blood and urinary 1,3-butadiene
Occupational exposure

ASJC Scopus subject areas

Toxicology

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10.1016/j.toxlet.2003.12.046

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abstract = "Exposure to 1,3-butadiene (BD), a probable carcinogen to humans, was investigated in two groups of subjects working in a petrochemical plant where BD is produced and used to prepare polymers: 42 occupationally exposed workers and 43 internal non-occupationally exposed controls. BD personal exposure was very low but significantly different in the two groups (median airborne BD 1.5 and 0.4μg/m3 in exposed and controls, respectively). Similarly, BD in blood and urine, but not in exhaled air, was higher in the exposed workers than in controls (blood BD 3.7ng/l versus ",

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AU - Fustinoni, S.

AU - Perbellini, L.

AU - Soleo, L.

AU - Manno, M.

AU - Foà, V.

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AB - Exposure to 1,3-butadiene (BD), a probable carcinogen to humans, was investigated in two groups of subjects working in a petrochemical plant where BD is produced and used to prepare polymers: 42 occupationally exposed workers and 43 internal non-occupationally exposed controls. BD personal exposure was very low but significantly different in the two groups (median airborne BD 1.5 and 0.4μg/m3 in exposed and controls, respectively). Similarly, BD in blood and urine, but not in exhaled air, was higher in the exposed workers than in controls (blood BD 3.7ng/l versus

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Biological monitoring in occupational exposure to low levels of 1,3-butadiene

Abstract

Keywords

ASJC Scopus subject areas

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