Biological monitoring in occupational exposure to low levels of 1,3-butadiene

S. Fustinoni, L. Perbellini, L. Soleo, M. Manno, V. Foà

Research output: Contribution to journalArticlepeer-review


Exposure to 1,3-butadiene (BD), a probable carcinogen to humans, was investigated in two groups of subjects working in a petrochemical plant where BD is produced and used to prepare polymers: 42 occupationally exposed workers and 43 internal non-occupationally exposed controls. BD personal exposure was very low but significantly different in the two groups (median airborne BD 1.5 and 0.4μg/m3 in exposed and controls, respectively). Similarly, BD in blood and urine, but not in exhaled air, was higher in the exposed workers than in controls (blood BD 3.7ng/l versus

Original languageEnglish
Pages (from-to)353-360
Number of pages8
JournalToxicology Letters
Issue number1-3
Publication statusPublished - Apr 1 2004


  • 1,3-Butadiene
  • Biomarkers
  • Blood and urinary 1,3-butadiene
  • Occupational exposure

ASJC Scopus subject areas

  • Toxicology


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