Biological monitoring of workers exposed to carbon tetrachloride vapor

Sergio Ghittori, Giannino Saretto, Marcello Imbriani

Research output: Contribution to journalArticle

Abstract

Occupational exposure to carbon tetrachloride was studied by analysis of environmental air, blood, and urine from 55 workers operating in two chemical plants where carbon tetrachloride was used. For the measurement of environmental concentration of carbon tetrachloride (Ci), the ambient air was sampled using personal passive dosimeters. The activated charcoal was desorbed with carbon disulfide and injected into a gas cromatograph-mass spectrometer (GC-MSD). The biological monitoring of exposed workers was conducted by determining the concentration of carbon tetrachloride in blood and urine. Urine and blood concentrations of carbon tetrachloride were determined by headspace analysis using GC-MSD. Significant correlations were found between the environmental carbon tetrachloride concentration and the blood and urinary concentrations. The use of a regression equation between Cu (ng/L) and C1 (mg/m3) (Cu = 125.7 × C1 + 56.2) result in a value of Cu corresponding to threshold limit value-time-weighted average exposure value (31 mg/m3 mg) of 3100 ng/L.

Original languageEnglish
Pages (from-to)353-357
Number of pages5
JournalApplied Occupational and Environmental Hygiene
Volume9
Issue number5
Publication statusPublished - May 1994

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Carbon Tetrachloride
Environmental Monitoring
Urine
Air
Threshold Limit Values
Carbon Disulfide
Charcoal
Occupational Exposure
Gases

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Biological monitoring of workers exposed to carbon tetrachloride vapor. / Ghittori, Sergio; Saretto, Giannino; Imbriani, Marcello.

In: Applied Occupational and Environmental Hygiene, Vol. 9, No. 5, 05.1994, p. 353-357.

Research output: Contribution to journalArticle

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