Biologics in Children with Allergic Diseases

Amelia Licari, Sara Manti, Alessia Marseglia, Maria De Filippo, Elisabetta De Sando, Thomas Foiadelli, Gian Luigi Marseglia

Research output: Contribution to journalArticlepeer-review

Abstract

The prevalence of allergic diseases has been remarkably increased in the last decades. The global health burden of these conditions is substantial, since patients may experience disability, anxiety and emotional distress, social restrictions, and reduced quality of life and productivity, in particular, in the most severe cases. Recent advances in understanding the pathophysiology of allergic disorders have allowed identifying novel therapeutic strategies for the treatment of severe and uncontrolled allergic diseases. Although most studies have been performed in allergic asthma, biological drugs targeting other allergic diseases such as chronic spontaneous urticaria, atopic dermatitis, and food allergy are showing promising results. In this review, the most recent evidence on biologic therapies for allergic diseases, focusing on the pediatric age has been presented.

Original languageEnglish
Pages (from-to)140-147
Number of pages8
JournalCurrent Pediatric Reviews
Volume16
Issue number2
DOIs
Publication statusPublished - 2020

Keywords

  • Asthma
  • atopic dermatitis
  • biologics
  • children
  • chronic spontaneous urticaria
  • food allergy.

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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