Biomarkers in neuroendocrine tumors

Massimiliano Berretta, Alessandro Cappellani, Maria Di Vita, Salvatore Berretta, Guglielmo Nasti, Alessandra Bearz, Umberto Tirelli, Vincenzo Canzonieri

Research output: Contribution to journalArticlepeer-review


Here we review the role of clinical biomarkers (tissue and circulating markers) in the management of neuroendocrine tumors. These tumors may originate in different organs, from cells embriologically different but expressing common phenotypic characteristics, such as the immuno-reactivity for markers of neuroendocrine differentiation (defined as "pan-neuroendocrine"), the capacity to secrete specific or aspecific peptide and hormones, and the expression of some receptors, that are at the basis of the current diagnostic and therapeutic approach.

Original languageEnglish
Pages (from-to)332-342
Number of pages11
JournalFrontiers in Bioscience - Scholar
Volume2 S
Issue number1
Publication statusPublished - Jan 1 2010


  • Cancer
  • Clinical Biomarkers
  • Diagnosis
  • Neuroendocrine tumors
  • Review

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Medicine(all)


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