Abstract
The use of 3D osteoconductive scaffolds provides an informative substrate serving as a physical support matrix for in vivo tissue regeneration. In the last few years the use of bioengineered 3D scaffolds has been becoming the most promising experimental approach for the regeneration of living tissues. Stem cells are typically used, in combination with 3D substrates, to promote in vivo bone regeneration and repair. For tissue engineering applications, biomaterials should therefore be able to support the functional properties of osteo-progenitor cells, giving them the optimal microenvironment to perform their physiological activity. Inorganic biomaterials are particularly relevant for bone regeneration; calcium phosphate ceramics have in fact been shown to strongly interact with bone tissue. The aim of the present work was to evaluate two different scaffolds with a defined design and different composition developed to guide/promote tissue repair.
| Original language | English |
|---|---|
| Pages (from-to) | 943-946 |
| Number of pages | 4 |
| Journal | Key Engineering Materials |
| Volume | 330-332 II |
| Publication status | Published - 2007 |
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Keywords
- Bone repair
- Calcium phosphates
- Scaffold
- Tissue engineering
ASJC Scopus subject areas
- Ceramics and Composites
- Chemical Engineering (miscellaneous)
Cite this
Biomimetic bone graft with higher bioactivity. / Martinetti, R.; Dolcini, L.; Merello, L.; Scaglione, S.; Quarto, R.; Pressato, D.
In: Key Engineering Materials, Vol. 330-332 II, 2007, p. 943-946.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Biomimetic bone graft with higher bioactivity
AU - Martinetti, R.
AU - Dolcini, L.
AU - Merello, L.
AU - Scaglione, S.
AU - Quarto, R.
AU - Pressato, D.
PY - 2007
Y1 - 2007
N2 - The use of 3D osteoconductive scaffolds provides an informative substrate serving as a physical support matrix for in vivo tissue regeneration. In the last few years the use of bioengineered 3D scaffolds has been becoming the most promising experimental approach for the regeneration of living tissues. Stem cells are typically used, in combination with 3D substrates, to promote in vivo bone regeneration and repair. For tissue engineering applications, biomaterials should therefore be able to support the functional properties of osteo-progenitor cells, giving them the optimal microenvironment to perform their physiological activity. Inorganic biomaterials are particularly relevant for bone regeneration; calcium phosphate ceramics have in fact been shown to strongly interact with bone tissue. The aim of the present work was to evaluate two different scaffolds with a defined design and different composition developed to guide/promote tissue repair.
AB - The use of 3D osteoconductive scaffolds provides an informative substrate serving as a physical support matrix for in vivo tissue regeneration. In the last few years the use of bioengineered 3D scaffolds has been becoming the most promising experimental approach for the regeneration of living tissues. Stem cells are typically used, in combination with 3D substrates, to promote in vivo bone regeneration and repair. For tissue engineering applications, biomaterials should therefore be able to support the functional properties of osteo-progenitor cells, giving them the optimal microenvironment to perform their physiological activity. Inorganic biomaterials are particularly relevant for bone regeneration; calcium phosphate ceramics have in fact been shown to strongly interact with bone tissue. The aim of the present work was to evaluate two different scaffolds with a defined design and different composition developed to guide/promote tissue repair.
KW - Bone repair
KW - Calcium phosphates
KW - Scaffold
KW - Tissue engineering
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UR - http://www.scopus.com/inward/citedby.url?scp=33846332747&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:33846332747
VL - 330-332 II
SP - 943
EP - 946
JO - Key Engineering Materials
JF - Key Engineering Materials
SN - 1013-9826
ER -