Comparison between the inhaled dose of pyrene by non-smoking subjects exposed to urban airborne contamination and the daily urinary excretion of the main metabolite 1-hydroxypyrene highlights a quantitative inconsistency, since the amount of the metabolite is 10-50 times higher than the inhaled dose of the parent compound. It is suggested that the excessive amount of hydroxypyrene may derive from the slow release of pyrene strongly absorbed or chemically embedded in the carbon soot deposited over a lifetime in the lung alveoli of the subject.
|Translated title of the contribution||Biomonitoring of exposure to pah: The pyrene vs. 1-hydroxypyrene paradox|
|Number of pages||2|
|Journal||Giornale Italiano di Medicina del Lavoro ed Ergonomia|
|Issue number||4 SUPPL.|
|Publication status||Published - 2004|
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health