Bipolar disorder and mania

Alberto Siracusano, Cinzia Niolu, Michele Ribolsi, Lucia Sacchetti

Research output: Chapter in Book/Report/Conference proceedingChapter


It has been emphasised elsewhere in this volume that depression is more frequent in MS patients than in the general population. The same goes for the prevalence of other psychiatric disorders and symptoms in the general population and in MS patients, and bipolar disorder (BD) is no exception, as has been repeatedly reported [1-3]. The BD prevalence rate estimated in MS patients in earlier reports is higher than that shown by more recent surveys (0.3 % to 32 % vs 0.3 % to 2.4 %) [1, 2; 4-7], the last values being supported by an estimate in a large population study [7]. The two to three times higher prevalence of BD in MS patients than in the general population which emerged from previous studies remains valid, as does the recently reported prevalence of BD in the general population of 0.24 % instead of the usually estimated 1 % [8].

Original languageEnglish
Title of host publicationNeuropsychiatric Dysfunction in Multiple Sclerosis
PublisherSpringer-Verlag Italia s.r.l.
Number of pages8
ISBN (Print)9788847026766, 884702675X, 9788847026759
Publication statusPublished - May 1 2012

ASJC Scopus subject areas

  • Medicine(all)


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