Bladder dose-surface maps and urinary toxicity: Robustness with respect to motion in assessing local dose effects

F. Palorini; A. Botti; V. Carillo; S. Gianolini; I. Improta; C. Iotti; T. Rancati; C. Cozzarini; C. Fiorino

doi:10.1016/j.ejmp.2016.03.006

Bladder dose-surface maps and urinary toxicity: Robustness with respect to motion in assessing local dose effects

F. Palorini, A. Botti, V. Carillo, S. Gianolini, I. Improta, C. Iotti, T. Rancati, C. Cozzarini, C. Fiorino

Research output: Contribution to journal › Article › peer-review

Abstract

The purpose of this study was to quantify the impact of inter-fraction modifications of bladder during RT of prostate cancer on bladder dose surface maps (DSM).Eighteen patients treated with daily image-guided Tomotherapy and moderate hypofractionation (70-72.8 Gy at 2.5-2.6 Gy/fr in 28 fractions and full bladder) were considered. Bladder contours were delineated on co-registered daily Megavoltage CT (MVCT) by a single observer and copied on the planning CT to generate dose-volume/surface histograms (DVH/DSH) and bladder DSMs. Discrepancies between planned and daily absorbed doses were analyzed through the average of individual systematic errors, the population systematic errors and the population random errors for the DVH/DSHs and DSMs.In total, 477 DVH/DSH and 472 DSM were available. DSH and DVH showed small population systematic errors of absolute surfaces (

Original language	English
Pages (from-to)	506 - 511
Number of pages	6
Journal	Physica Medica
Volume	32
Issue number	3
DOIs	https://doi.org/10.1016/j.ejmp.2016.03.006
Publication status	Published - Mar 1 2016

Keywords

Bladder
Dose-surface maps
Inter-fraction motion

ASJC Scopus subject areas

Biophysics
Radiology Nuclear Medicine and imaging
Physics and Astronomy(all)

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10.1016/j.ejmp.2016.03.006

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title = "Bladder dose-surface maps and urinary toxicity: Robustness with respect to motion in assessing local dose effects",

abstract = "The purpose of this study was to quantify the impact of inter-fraction modifications of bladder during RT of prostate cancer on bladder dose surface maps (DSM).Eighteen patients treated with daily image-guided Tomotherapy and moderate hypofractionation (70-72.8 Gy at 2.5-2.6 Gy/fr in 28 fractions and full bladder) were considered. Bladder contours were delineated on co-registered daily Megavoltage CT (MVCT) by a single observer and copied on the planning CT to generate dose-volume/surface histograms (DVH/DSH) and bladder DSMs. Discrepancies between planned and daily absorbed doses were analyzed through the average of individual systematic errors, the population systematic errors and the population random errors for the DVH/DSHs and DSMs.In total, 477 DVH/DSH and 472 DSM were available. DSH and DVH showed small population systematic errors of absolute surfaces (",

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AU - Palorini, F.

AU - Botti, A.

AU - Carillo, V.

AU - Gianolini, S.

AU - Improta, I.

AU - Iotti, C.

AU - Rancati, T.

AU - Cozzarini, C.

AU - Fiorino, C.

PY - 2016/3/1

Y1 - 2016/3/1

N2 - The purpose of this study was to quantify the impact of inter-fraction modifications of bladder during RT of prostate cancer on bladder dose surface maps (DSM).Eighteen patients treated with daily image-guided Tomotherapy and moderate hypofractionation (70-72.8 Gy at 2.5-2.6 Gy/fr in 28 fractions and full bladder) were considered. Bladder contours were delineated on co-registered daily Megavoltage CT (MVCT) by a single observer and copied on the planning CT to generate dose-volume/surface histograms (DVH/DSH) and bladder DSMs. Discrepancies between planned and daily absorbed doses were analyzed through the average of individual systematic errors, the population systematic errors and the population random errors for the DVH/DSHs and DSMs.In total, 477 DVH/DSH and 472 DSM were available. DSH and DVH showed small population systematic errors of absolute surfaces (

AB - The purpose of this study was to quantify the impact of inter-fraction modifications of bladder during RT of prostate cancer on bladder dose surface maps (DSM).Eighteen patients treated with daily image-guided Tomotherapy and moderate hypofractionation (70-72.8 Gy at 2.5-2.6 Gy/fr in 28 fractions and full bladder) were considered. Bladder contours were delineated on co-registered daily Megavoltage CT (MVCT) by a single observer and copied on the planning CT to generate dose-volume/surface histograms (DVH/DSH) and bladder DSMs. Discrepancies between planned and daily absorbed doses were analyzed through the average of individual systematic errors, the population systematic errors and the population random errors for the DVH/DSHs and DSMs.In total, 477 DVH/DSH and 472 DSM were available. DSH and DVH showed small population systematic errors of absolute surfaces (

KW - Bladder

KW - Dose-surface maps

KW - Inter-fraction motion

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JF - Physica Medica

SN - 1120-1797

IS - 3

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Bladder dose-surface maps and urinary toxicity: Robustness with respect to motion in assessing local dose effects

Abstract

Keywords

ASJC Scopus subject areas

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