Bladder dose-surface maps and urinary toxicity: Robustness with respect to motion in assessing local dose effects

F. Palorini, A. Botti, V. Carillo, S. Gianolini, I. Improta, C. Iotti, T. Rancati, C. Cozzarini, C. Fiorino

Research output: Contribution to journalArticle

Abstract

The purpose of this study was to quantify the impact of inter-fraction modifications of bladder during RT of prostate cancer on bladder dose surface maps (DSM).Eighteen patients treated with daily image-guided Tomotherapy and moderate hypofractionation (70-72.8 Gy at 2.5-2.6 Gy/fr in 28 fractions and full bladder) were considered. Bladder contours were delineated on co-registered daily Megavoltage CT (MVCT) by a single observer and copied on the planning CT to generate dose-volume/surface histograms (DVH/DSH) and bladder DSMs. Discrepancies between planned and daily absorbed doses were analyzed through the average of individual systematic errors, the population systematic errors and the population random errors for the DVH/DSHs and DSMs.In total, 477 DVH/DSH and 472 DSM were available. DSH and DVH showed small population systematic errors of absolute surfaces (
Original languageEnglish
Pages (from-to)506 - 511
Number of pages6
JournalPhysica Medica
Volume32
Issue number3
DOIs
Publication statusPublished - Mar 1 2016

Keywords

  • Bladder
  • Dose-surface maps
  • Inter-fraction motion

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging
  • Physics and Astronomy(all)

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