Influencia del tipo de cobertura prenatal sobre el desarrollo vesical en un modelo de mielomeningocele.

Translated title of the contribution: [Bladder malformations in a model of myelomeningocele. Preliminary report].

J. L. Encinas, M. Germani, L. Burgos, C. Soto, F. Pederiva, A. Luis, L. F. Avila, M. A. García-Cabezas, J. L. Peiró, R. Rodríguez, M. López-Santamaría, J. A. Tovar

Research output: Contribution to journalArticlepeer-review

Abstract

To describe the presence of bladder malformations in a surgically induced model of myelomeningocele (MMC). A MMC like defect was created in the mid gestation using the previously described model in sheep. Bladders were examined macroscopically and histopathological changes were assessed using H-E. Non prenatally corrected animals presented dilated bladders and separation between muscle bundles. Those malformations were not found in corrected animals or controls. Some bladder changes can be described in a surgically-induced model of MMC. These changes could be prevented using open fetal surgery.

Translated title of the contribution[Bladder malformations in a model of myelomeningocele. Preliminary report].
Original languageSpanish
Pages (from-to)122-125
Number of pages4
JournalCirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica
Volume23
Issue number2
Publication statusPublished - Apr 2010

ASJC Scopus subject areas

  • Medicine(all)

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