To describe the presence of bladder malformations in a surgically induced model of myelomeningocele (MMC). A MMC like defect was created in the mid gestation using the previously described model in sheep. Bladders were examined macroscopically and histopathological changes were assessed using H-E. Non prenatally corrected animals presented dilated bladders and separation between muscle bundles. Those malformations were not found in corrected animals or controls. Some bladder changes can be described in a surgically-induced model of MMC. These changes could be prevented using open fetal surgery.
|Translated title of the contribution||[Bladder malformations in a model of myelomeningocele. Preliminary report].|
|Number of pages||4|
|Journal||Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica|
|Publication status||Published - Apr 2010|
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