Abstract
Renal insufficiency is associated with a bleeding tendency. Hemorrhagic manifestations are usually mild (i.e., ecchymoses or purpura) but can be severe in occasional patients who may have gastrointestinal tract or intracranial bleeding. Modern techniques for the management of uremia have definitely reduced the incidence of severe bleeding episodes in patients with renal failure, but hemorrhages still represent a major clinical problem, particularly for patients undergoing surgery or invasive procedures. Although the pathogenesis of uremic bleeding has not been completely elucidated, in the past 10 years a number of studies have contributed substantially to our knowledge of the cause of uremic bleeding tendency and have indicated new therapeutic strategies. The present review will focus mainly on modern concepts of the cause of uremic bleeding and will critically analyze the various therapeutic approaches.
| Original language | English |
|---|---|
| Pages (from-to) | 171-186 |
| Number of pages | 16 |
| Journal | Advances in nephrology from the Necker Hospital |
| Volume | 18 |
| Publication status | Published - 1989 |
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ASJC Scopus subject areas
- Medicine(all)
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Bleeding disorders in uremia : pathophysiology and treatment. / Remuzzi, G.
In: Advances in nephrology from the Necker Hospital, Vol. 18, 1989, p. 171-186.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Bleeding disorders in uremia
T2 - pathophysiology and treatment.
AU - Remuzzi, G.
PY - 1989
Y1 - 1989
N2 - Renal insufficiency is associated with a bleeding tendency. Hemorrhagic manifestations are usually mild (i.e., ecchymoses or purpura) but can be severe in occasional patients who may have gastrointestinal tract or intracranial bleeding. Modern techniques for the management of uremia have definitely reduced the incidence of severe bleeding episodes in patients with renal failure, but hemorrhages still represent a major clinical problem, particularly for patients undergoing surgery or invasive procedures. Although the pathogenesis of uremic bleeding has not been completely elucidated, in the past 10 years a number of studies have contributed substantially to our knowledge of the cause of uremic bleeding tendency and have indicated new therapeutic strategies. The present review will focus mainly on modern concepts of the cause of uremic bleeding and will critically analyze the various therapeutic approaches.
AB - Renal insufficiency is associated with a bleeding tendency. Hemorrhagic manifestations are usually mild (i.e., ecchymoses or purpura) but can be severe in occasional patients who may have gastrointestinal tract or intracranial bleeding. Modern techniques for the management of uremia have definitely reduced the incidence of severe bleeding episodes in patients with renal failure, but hemorrhages still represent a major clinical problem, particularly for patients undergoing surgery or invasive procedures. Although the pathogenesis of uremic bleeding has not been completely elucidated, in the past 10 years a number of studies have contributed substantially to our knowledge of the cause of uremic bleeding tendency and have indicated new therapeutic strategies. The present review will focus mainly on modern concepts of the cause of uremic bleeding and will critically analyze the various therapeutic approaches.
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M3 - Article
C2 - 2493714
AN - SCOPUS:0024587888
VL - 18
SP - 171
EP - 186
JO - Advances in nephrology from the Necker Hospital
JF - Advances in nephrology from the Necker Hospital
SN - 0084-5957
ER -