Bleeding in renal failure: altered platelet function in chronic uraemia only partially corrected by haemodialysis

G. Remuzzi, M. Livio, G. Marchiaro, G. Mecca, G. de Gaetano

Research output: Contribution to journalArticle

103 Citations (Scopus)

Abstract

Bleeding time, blood loss and platelet retention by glass beads, measured by standardized techniques, were significantly altered in a group of 30 non-thrombocytopenic patients with chronic renal failure undergoing maintenance hemodialysis. Bleeding time or blood loss did not correlate with platelet retention either before or after haemodialysis. No correlation could be found between the above tests and a number of biochemical parameters characterizing the uremic condition. Haemodialysis only partially corrected the abnormal bleeding time, blood loss and platelet retention. These tests were still significantly different after haemodialysis from those of 30 normal subjects. It is suggested that some non-dialyzable material could play an important role in the aetiology of uremic bleeding.

Original languageEnglish
Pages (from-to)347-353
Number of pages7
JournalNephron
Volume22
Issue number4-6
Publication statusPublished - 1978

Fingerprint

Uremia
Bleeding Time
Renal Insufficiency
Renal Dialysis
Blood Platelets
Hemorrhage
Chronic Kidney Failure
Glass
Maintenance

ASJC Scopus subject areas

  • Nephrology

Cite this

Bleeding in renal failure : altered platelet function in chronic uraemia only partially corrected by haemodialysis. / Remuzzi, G.; Livio, M.; Marchiaro, G.; Mecca, G.; de Gaetano, G.

In: Nephron, Vol. 22, No. 4-6, 1978, p. 347-353.

Research output: Contribution to journalArticle

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