Blocking of morphine-induced locomotor hyperactivity by amygdaloid lesions in C57BL/6 mice

Vincenzo Libri, Martine Ammassari-Teule, Claudio Castellano

Research output: Contribution to journalArticlepeer-review

Abstract

Bilateral lesions of the amygdaloid complex in C57BL/6 mice prevented the occurrence of morphine-induced hypermotility (running fit). This effect, that was different from that observed after hippocampal lesions but similar to that observed after caudate lesions, confirms the role of the basal ganglia catecholaminergic system in the development of the motor stimulation consecutive to the administration of this opiate receptor agonist.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalBrain Research
Volume479
Issue number1
DOIs
Publication statusPublished - Feb 6 1989

Keywords

  • Amygdala
  • C57BL/6 mouse
  • Caudate nucleus
  • Hippocampus
  • Lesion
  • Locomotor activity
  • Morphine

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Blocking of morphine-induced locomotor hyperactivity by amygdaloid lesions in C57BL/6 mice'. Together they form a unique fingerprint.

Cite this