Blood glucose monitoring in the normal population: The PREDICA study

N. Napoli, F. Costanza, E. Di Stasio, R. Strollo, S. Manfrini, E. Cipponeri, A. Picardi, F. Carrano, V. Dell'Anna, W. MacIno, P. Pozzilli

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Abstract

In the PREdiction of DIabetes from CApillary blood glucose (PREDICA) study, we propose a novel approach based on multiple capillary blood glucose (CBG) measurements, assuming that weekly measurements performed for 2 months may be an efficient strategy to screen for diabetes. We studied 538 Caucasian subjects (247 men and 291 women) without a history of diabetes, consecutively recruited by 50 GPs from the Italian provinces of Rome and Frosinone. Subjects were asked to perform 8 fasting glucose and 8 post-prandial glucose measurements during a frame time of 2 months (Glucometer Accu-chek AVIVA Roche Diagnostics). Study subjects were 55 ± 9 years old (range 22-77 years of age), 50% were overweight and 16% obese. Fifty-eight percent of subjects have performed 13 to 16 CBG measurements during the study, 68% of subjects have performed at least 5 out of 8, both fasting and post-prandial measurements. Among 492 subjects who had at least two fasting measurements, 63.6% had normal glucose levels, 25.4% showed IFG, and 11.0% were diabetic. Considering post-prandial measurements, 74.2% had normal glucose levels, 23.0% had IGT, and 2.8% were diabetic. Combined IFG + IGT was detected in 7% of study subjects, while in 0.8% diagnosis of diabetes was confirmed with both fasting and post-prandial measurements. In this study, we found a high adherence to a novel screening strategy based on self-glucose monitoring in the general population. Our results show that multiple CBG measurements may represent a simple and efficient method for diabetes screening.

Original languageEnglish
Pages (from-to)29-34
Number of pages6
JournalActa Diabetologica
Volume48
Issue number1
DOIs
Publication statusPublished - Mar 2011

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Keywords

  • Capillary blood glucose
  • Diabetes screening
  • Pre-diabetes
  • Self-monitoring blood glucose
  • Undiagnosed diabetes

ASJC Scopus subject areas

  • Endocrinology
  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

Cite this

Napoli, N., Costanza, F., Di Stasio, E., Strollo, R., Manfrini, S., Cipponeri, E., Picardi, A., Carrano, F., Dell'Anna, V., MacIno, W., & Pozzilli, P. (2011). Blood glucose monitoring in the normal population: The PREDICA study. Acta Diabetologica, 48(1), 29-34. https://doi.org/10.1007/s00592-010-0212-6