TY - JOUR
T1 - Blood levels of vitamin E, polyunsaturated fatty acids of phospholipids, lipoperoxides and glutathione peroxidase in patients affected with seborrheic dermatitis
AU - Passi, S.
AU - Morrone, A.
AU - De Luca, C.
AU - Picardo, M.
AU - Ippolito, F.
PY - 1991
Y1 - 1991
N2 - Plasma levels of vitamin E (Vit E) and polyunsaturated fatty acids of phospholipids (PUFA-PL) as well as erythrocyte glutathione peroxidase (GSH-Px) activity are significantly lower (P <0.001) in patients with seborrheic dermatitis (SD), both HIV sero-positive or HIV sero-negative, than in control subjects. No differences are found between HIV sero-positive and sero-negative individuals with SD. The deficiency of PUFA-PL (mainly C20: 3 n-6, C20: 4 n-6 and C22: 6 n-3) which is accompanied by a significant increase of saturated palmitic and stearic acids (P <0.001), does not appear to be associated with an active lipoperoxidative process in the plasma. The significant blood deficiency of Vit E, GSH-Px, and particularly of PUFA-PL, may play a pathogenetic role in seborrheic dermatitis.
AB - Plasma levels of vitamin E (Vit E) and polyunsaturated fatty acids of phospholipids (PUFA-PL) as well as erythrocyte glutathione peroxidase (GSH-Px) activity are significantly lower (P <0.001) in patients with seborrheic dermatitis (SD), both HIV sero-positive or HIV sero-negative, than in control subjects. No differences are found between HIV sero-positive and sero-negative individuals with SD. The deficiency of PUFA-PL (mainly C20: 3 n-6, C20: 4 n-6 and C22: 6 n-3) which is accompanied by a significant increase of saturated palmitic and stearic acids (P <0.001), does not appear to be associated with an active lipoperoxidative process in the plasma. The significant blood deficiency of Vit E, GSH-Px, and particularly of PUFA-PL, may play a pathogenetic role in seborrheic dermatitis.
KW - AIDS
KW - Glutathione peroxidase
KW - Lipoperoxides
KW - Phospholipids
KW - Polyunsaturated fatty acids
KW - Seborrheic dermatitis
KW - Vitamin E
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U2 - 10.1016/0923-1811(91)90064-5
DO - 10.1016/0923-1811(91)90064-5
M3 - Article
C2 - 1831657
AN - SCOPUS:0025806353
VL - 2
SP - 171
EP - 178
JO - Journal of Dermatological Science
JF - Journal of Dermatological Science
SN - 0923-1811
IS - 3
ER -