Blood loss during transvaginal oocyte retrieval

Guido Ragni, Claudia Scarduelli, Graziella Calanna, Giulia Santi, Laura Benaglia, Edgardo Somigliana

Research output: Contribution to journalArticlepeer-review


Background/Aims: Limited information is available regarding the quantity of blood loss associated with uncomplicated transvaginal oocyte retrieval. The aim of the present study was evaluating the quantity of such a loss. Methods: One hundred and fifty consecutive women undergoing oocyte retrieval were recruited. They underwent blood test assessment and ultrasonographic transvaginal evaluation at three different times: (1) immediately before initiating oocyte retrieval, (2) 4-6 h later, and (3) 72 h later. Results: At 4-6 h after oocyte retrieval, the red blood cell count and the hemoglobin concentration were significantly reduced, whereas pelvic free fluid had significantly increased. The estimated median (Interquartile range) blood loss was 72 (-8/162) ml. None of the recruited women was found to have a hemoglobin reduction >2 g/day or an increase in the pelvic free fluid >200 ml or a calculated blood loss >500 ml (0.0%, 95% CI: 0.0-2.4%). No significant worsening from baseline was observed at the 72 h evaluation. Conclusions: The quantity of blood loss following oocyte retrieval is clinically unremarkable in the vast majority of women.

Original languageEnglish
Pages (from-to)32-35
Number of pages4
JournalGynecologic and Obstetric Investigation
Issue number1
Publication statusPublished - Jan 2009


  • Blood loss
  • Hemoglobin
  • In vitro fertilization
  • Oocyte retrieval
  • Red blood cell

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Reproductive Medicine

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