Blood pressure and antihypertensive therapy according to the global cardiovascular risk level in Italy: The CHECK Study

Alessandro Filippi, Manuela Casula, Elena Tragni, Ovidio Brignoli, Claudio Cricelli, Andrea Poli, Alberico Luigi Catapano

Research output: Contribution to journalArticle

Abstract

Background: Elevated blood pressure (BP) is one of the most important modifiable risk factors for cardiovascular diseases. In this study we assessed the excess of cardiovascular risk attributable to high BP and antihypertensive treatment in a sample of Italian patients enrolled by the 'Cholesterol and Health: Education, Control and Knowledge' (CHECK) study. Methods: CHECK is a large, cross-sectional epidemiological study, which randomly enrolled patients aged 40-79 years from 425 Italian General Practices from March 2002 to April 2004. Among 5731 patients enrolled in the study [49.6% men, mean age (standard deviation) 57.7 (10.3) years], 723 (12.6%) had 'optimal' BP, 1496 (26.1%) had 'high normal' BP, and 1942 (33.9%) were hypertensive. Results: According to the European Guidelines stratification of the cardiovascular risk-excess attributable to high BP, 34.7% of the sample had a low added risk and 53.2% had a moderate-to-very high added risk. The pharmacological therapy was prescribed in 22.3, 43.9, 61.4, and 76.9% of the patients with low, moderate, high, and very high added risk, respectively. Conclusion: Overall dietary and drug therapies are under prescribed, as most of the treated patients would require two additional antihypertensive drugs to meet the recommended BP target. This effort could provide significant individual benefit to moderate/high-risk patients.

Original languageEnglish
Pages (from-to)562-568
Number of pages7
JournalEuropean Journal of Cardiovascular Prevention and Rehabilitation
Volume17
Issue number5
DOIs
Publication statusPublished - Oct 2010

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Health Education
Antihypertensive Agents
Italy
Cholesterol
Blood Pressure
Hypertension
Therapeutics
General Practice
Epidemiologic Studies
Cardiovascular Diseases
Cross-Sectional Studies
Pharmacology
Guidelines
Drug Therapy

Keywords

  • Antihypertensive therapy
  • blood pressure
  • cardiovascular risk
  • epidemiology
  • primary care

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Epidemiology

Cite this

Blood pressure and antihypertensive therapy according to the global cardiovascular risk level in Italy : The CHECK Study. / Filippi, Alessandro; Casula, Manuela; Tragni, Elena; Brignoli, Ovidio; Cricelli, Claudio; Poli, Andrea; Catapano, Alberico Luigi.

In: European Journal of Cardiovascular Prevention and Rehabilitation, Vol. 17, No. 5, 10.2010, p. 562-568.

Research output: Contribution to journalArticle

Filippi, Alessandro ; Casula, Manuela ; Tragni, Elena ; Brignoli, Ovidio ; Cricelli, Claudio ; Poli, Andrea ; Catapano, Alberico Luigi. / Blood pressure and antihypertensive therapy according to the global cardiovascular risk level in Italy : The CHECK Study. In: European Journal of Cardiovascular Prevention and Rehabilitation. 2010 ; Vol. 17, No. 5. pp. 562-568.
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