TY - JOUR
T1 - Blood pressure control and treatment adherence in hypertensive patients with metabolic syndrome
T2 - Protocol of a randomized controlled study based on home blood pressure telemonitoring vs. conventional management and assessment of psychological determinants of adherence (TELEBPMET Study)
AU - Parati, Gianfranco
AU - Omboni, Stefano
AU - Compare, Angelo
AU - Grossi, Enzo
AU - Callus, Edward
AU - Venco, Achille
AU - Destro, Maurizio
AU - Villa, Giuseppe
AU - Palatini, Paolo
AU - Rosei, Enrico Agabiti
AU - Scalvini, Simonetta
AU - Taddei, Stefano
AU - Manfellotto, Dario
AU - Favale, Stefano
AU - De Matteis, Carmine
AU - Guglielmi, Michele
PY - 2013/1/23
Y1 - 2013/1/23
N2 - Background: Inadequate blood pressure control and poor adherence to treatment remain among the major limitations in the management of hypertensive patients, particularly of those at high risk of cardiovascular events. Preliminary evidence suggests that home blood pressure telemonitoring (HBPT) might help increasing the chance of achieving blood pressure targets and improve patient's therapeutic adherence. However, all these potential advantages of HBPT have not yet been fully investigated.Methods/design: The purpose of this open label, parallel group, randomized, controlled study is to assess whether, in patients with high cardiovascular risk (treated or untreated essential arterial hypertension - both in the office and in ambulatory conditions over 24 h - and metabolic syndrome), long-term (48 weeks) blood pressure control is more effective when based on HBPT and on the feedback to patients by their doctor between visits, or when based exclusively on blood pressure determination during quarterly office visits (conventional management (CM)). A total of 252 patients will be enrolled and randomized to usual care (n=84) or HBPT (n=168). The primary study endpoint will be the rate of subjects achieving normal daytime ambulatory blood pressure targets (
AB - Background: Inadequate blood pressure control and poor adherence to treatment remain among the major limitations in the management of hypertensive patients, particularly of those at high risk of cardiovascular events. Preliminary evidence suggests that home blood pressure telemonitoring (HBPT) might help increasing the chance of achieving blood pressure targets and improve patient's therapeutic adherence. However, all these potential advantages of HBPT have not yet been fully investigated.Methods/design: The purpose of this open label, parallel group, randomized, controlled study is to assess whether, in patients with high cardiovascular risk (treated or untreated essential arterial hypertension - both in the office and in ambulatory conditions over 24 h - and metabolic syndrome), long-term (48 weeks) blood pressure control is more effective when based on HBPT and on the feedback to patients by their doctor between visits, or when based exclusively on blood pressure determination during quarterly office visits (conventional management (CM)). A total of 252 patients will be enrolled and randomized to usual care (n=84) or HBPT (n=168). The primary study endpoint will be the rate of subjects achieving normal daytime ambulatory blood pressure targets (
KW - Adherence
KW - Anxiety
KW - Blood pressure
KW - Depression
KW - Home blood pressure telemonitoring
KW - Hypertension
KW - Personality traits
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U2 - 10.1186/1745-6215-14-22
DO - 10.1186/1745-6215-14-22
M3 - Article
C2 - 23343138
AN - SCOPUS:84872579090
VL - 14
JO - Trials
JF - Trials
SN - 1745-6215
IS - 1
M1 - 22
ER -