Blood pressure regulation mechanisms: The role of the sympathetic nervous and renin angiotensin systems in patients on salt-free diets

G. Lembo, C. Autiero, A. Morganti, A. Ricci, M. Volpe, M. Condorelli

Research output: Contribution to journalArticle

Abstract

In order to discover more about the role of the sympathetic nervous and renin-angiotensin systems in the preservation of homeostasis during chronic reductions of salt intake, blood pressure, blood catecholamines and renin activity were measured in a group of healthy subjects in normal conditions and on a salt-free diet combined with blockade of the conversion enzyme by enalapril. The results confirmed the hypothesis advanced on an earlier occasion i.e. that both hormone systems contribute to pressure during salt depletion in the initial phase, while over the long term only the renin-angiotensin system is activated though when this is inhibited, the sympathetic nervous system will take over its function.

Original languageEnglish
Pages (from-to)1745-1752
Number of pages8
JournalMinerva Medica
Volume78
Issue number23
Publication statusPublished - 1987

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ASJC Scopus subject areas

  • Medicine(all)

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