Blood pressure status and the incidence of diabetic kidney disease in patients with hypertension and type 2 diabetes

Salvatore De Cosmo, Francesca Viazzi, Pamela Angela Piscitelli, Carlo Giorda, Antonio Ceriello, Stefano Genovese, Giuseppina Russo, Pietro Guida, Paola Fioretto, Roberto Pontremoli

Research output: Contribution to journalArticle

Abstract

OBJECTIVE:: Antihypertensive treatment and blood pressure (BP) reduction are known to retard the progression of diabetic kidney disease (DKD) in type 2 diabetes mellitus (T2DM) but long-term real-life clinical data on the incidence of DKD are lacking. In this observational, prospective cohort study, we investigated the association between achievement and maintenance of recommended BP values and the incidence of DKD and its components over a 4-year follow-up in patients with T2DM and hypertension from the Italian Medical Diabetologists registry. METHODS:: Clinical records from a total of 12?995 patients with normal renal function and urine albumin excretion at baseline and regular visits during a 4-year follow-up were retrieved and analyzed. The association between recommended, time-updated BP control (BPC) (i.e. ≥75% of visits with SBP and DBP

Original languageEnglish
JournalJournal of Hypertension
DOIs
Publication statusAccepted/In press - Jul 21 2016

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

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