Body composition in HIV-infected children: Relations with disease progression and survival

Massimo Fontana, Giovanna Zuin, Anna Plebani, Ketty Bastoni, Giovanna Visconti, Nicola Principi

Research output: Contribution to journalArticlepeer-review


Background: Malnutrition is common in HIV-infected children, but the body compartment that is most affected has been ill defined. Objectives: Our objectives were to 1) compare the fat-free mass (FFM) of children with HIV infection with that of control children, 2) assess the contribution of FFM to body weight in HIV-infected children compared with that of control children, and 3) study the relations between body weight, FFM, and mortality. Design: A cross-sectional study was performed in 86 HIV-infected and 113 uninfected children (mean ages: 6.9 and 7.7 y, respectively). FFM was estimated from single-frequency bioelectrical impedance analysis by using 3 different published equations; a further estimate was obtained from triceps-skinfold- thickness measurements. Results: All 4 estimates of body composition showed that FFM in HIV-infected children was significantly less than in control children of similar age. However, FFM as a percentage of body weight was not significantly different between groups. In the whole group of infected children, an age-specific z score

Original languageEnglish
Pages (from-to)1282-1286
Number of pages5
JournalAmerican Journal of Clinical Nutrition
Issue number6
Publication statusPublished - Jun 1999


  • Acquired immune deficiency syndrome
  • AIDS
  • Bioelectrical impedance analysis
  • Body composition
  • Cachexia
  • Children
  • Fat-free mass
  • HIV
  • Human immunodeficiency virus
  • Lean body mass
  • Malnutrition
  • Prognosis
  • Survival
  • Wasting syndrome

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)


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