Body mass index, cognition, disability, APOE genotype, and mortality: The "treviso longeva" study

Deborah R. Gustafson, Stephano Mazzuco, Fausta Ongaro, Piero Antuono, Gianluigi Forloni, Diego Albani, Gian Battista Gajo, Elisabetta Durante, Livio Caberlotto, Andrea Zanardo, Marinella Siculi, Maurizio Gallucci

Research output: Contribution to journalArticlepeer-review


Objectives: The concurrent contributions of dynamic, interrelated late-life parameters, such as body mass index (BMI), cognition, and physical functioning on mortality in the elderly are unclear, as is the influence of APOE genotype. We explored these measures in relation to 7-year mortality in long-lived Italian elderly. Design: A representative, age-stratified, population sample. Setting: The Treviso Longeva (TRELONG) Study, in Treviso, Italy. Participants: Three hundred eleven men and 357 women, aged 70 years and older (mean age 84 ± 8 years). Measurements: Seven-year mortality, BMI, Mini-Mental State Examination (MMSE) score, Activities of Daily Living (ADL), APOE genotype, and a variety of clinical and survey data. Results: In separate age-and sex-adjusted analyses, BMI

Original languageEnglish
Pages (from-to)594-602
Number of pages9
JournalAmerican Journal of Geriatric Psychiatry
Issue number7
Publication statusPublished - Jul 2012


  • ADL
  • APOE
  • BMI
  • cognition
  • mortality

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Geriatrics and Gerontology


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