Body weight changes in a large cohort of patients subjected to thyroidectomy for a wide spectrum of thyroid diseases

Mario Rotondi; Laura Croce; Cristina Pallavicini; Luigi La Manna; Silvia Accornero; Rodolfo Fonte; Flavia Magri; Luca Chiovato

doi:10.4158/EP14125.OR

Body weight changes in a large cohort of patients subjected to thyroidectomy for a wide spectrum of thyroid diseases

Mario Rotondi, Laura Croce, Cristina Pallavicini, Luigi La Manna, Silvia Accornero, Rodolfo Fonte, Flavia Magri, Luca Chiovato

Istituti Clinici Scientifici Maugeri Spa – Società Benefit

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: Patients undergoing thyroidectomy often complain of weight gain. The aim of this study was to longitudinally evaluate body-weight changes in patients thyroidectomized for euthyroid and hyperthyroid conditions in order to identify predictive factors.

Methods: Anthropometric data and thyroid function parameters were retrospectively reviewed for 267 thyroidectomized patients before and 40 to 60 days and 9 months after surgery. Presurgery diagnoses included benign (Graves disease, nodular toxic goiter, nodular nontoxic goiter) and malignant (differentiated thyroid cancer) conditions.

Results: Mean preintervention weight of the entire study group significantly increased (P

Conclusion: Thyroidectomy is associated with a significant increase in body weight, which is not limited to patients with Graves disease. Postsurgery TSH levels do not account for subsequent body-weight changes. Short-term changes (40 to 60 days postsurgery) in body weight are highly predictive of the outcome at 9 months, suggesting that early factors related to thyroidectomy per se might play a role.

Original language	English
Pages (from-to)	1151-1158
Number of pages	8
Journal	Endocrine Practice
Volume	20
Issue number	11
DOIs	https://doi.org/10.4158/EP14125.OR
Publication status	Published - Nov 1 2014

ASJC Scopus subject areas

Endocrinology
Endocrinology, Diabetes and Metabolism

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Body weight changes in a large cohort of patients subjected to thyroidectomy for a wide spectrum of thyroid diseases. / Rotondi, Mario; Croce, Laura; Pallavicini, Cristina; Manna, Luigi La; Accornero, Silvia; Fonte, Rodolfo; Magri, Flavia ; Chiovato, Luca.

In: Endocrine Practice, Vol. 20, No. 11, 01.11.2014, p. 1151-1158.

Research output: Contribution to journal › Article › peer-review

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abstract = "Objective: Patients undergoing thyroidectomy often complain of weight gain. The aim of this study was to longitudinally evaluate body-weight changes in patients thyroidectomized for euthyroid and hyperthyroid conditions in order to identify predictive factors.Methods: Anthropometric data and thyroid function parameters were retrospectively reviewed for 267 thyroidectomized patients before and 40 to 60 days and 9 months after surgery. Presurgery diagnoses included benign (Graves disease, nodular toxic goiter, nodular nontoxic goiter) and malignant (differentiated thyroid cancer) conditions.Results: Mean preintervention weight of the entire study group significantly increased (PConclusion: Thyroidectomy is associated with a significant increase in body weight, which is not limited to patients with Graves disease. Postsurgery TSH levels do not account for subsequent body-weight changes. Short-term changes (40 to 60 days postsurgery) in body weight are highly predictive of the outcome at 9 months, suggesting that early factors related to thyroidectomy per se might play a role.",

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AU - Accornero, Silvia

AU - Fonte, Rodolfo

AU - Magri, Flavia

AU - Chiovato, Luca

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N2 - Objective: Patients undergoing thyroidectomy often complain of weight gain. The aim of this study was to longitudinally evaluate body-weight changes in patients thyroidectomized for euthyroid and hyperthyroid conditions in order to identify predictive factors.Methods: Anthropometric data and thyroid function parameters were retrospectively reviewed for 267 thyroidectomized patients before and 40 to 60 days and 9 months after surgery. Presurgery diagnoses included benign (Graves disease, nodular toxic goiter, nodular nontoxic goiter) and malignant (differentiated thyroid cancer) conditions.Results: Mean preintervention weight of the entire study group significantly increased (PConclusion: Thyroidectomy is associated with a significant increase in body weight, which is not limited to patients with Graves disease. Postsurgery TSH levels do not account for subsequent body-weight changes. Short-term changes (40 to 60 days postsurgery) in body weight are highly predictive of the outcome at 9 months, suggesting that early factors related to thyroidectomy per se might play a role.

AB - Objective: Patients undergoing thyroidectomy often complain of weight gain. The aim of this study was to longitudinally evaluate body-weight changes in patients thyroidectomized for euthyroid and hyperthyroid conditions in order to identify predictive factors.Methods: Anthropometric data and thyroid function parameters were retrospectively reviewed for 267 thyroidectomized patients before and 40 to 60 days and 9 months after surgery. Presurgery diagnoses included benign (Graves disease, nodular toxic goiter, nodular nontoxic goiter) and malignant (differentiated thyroid cancer) conditions.Results: Mean preintervention weight of the entire study group significantly increased (PConclusion: Thyroidectomy is associated with a significant increase in body weight, which is not limited to patients with Graves disease. Postsurgery TSH levels do not account for subsequent body-weight changes. Short-term changes (40 to 60 days postsurgery) in body weight are highly predictive of the outcome at 9 months, suggesting that early factors related to thyroidectomy per se might play a role.

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