Body weight changes in a large cohort of patients subjected to thyroidectomy for a wide spectrum of thyroid diseases

Mario Rotondi, Laura Croce, Cristina Pallavicini, Luigi La Manna, Silvia Accornero, Rodolfo Fonte, Flavia Magri, Luca Chiovato

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: Patients undergoing thyroidectomy often complain of weight gain. The aim of this study was to longitudinally evaluate body-weight changes in patients thyroidectomized for euthyroid and hyperthyroid conditions in order to identify predictive factors.

Methods: Anthropometric data and thyroid function parameters were retrospectively reviewed for 267 thyroidectomized patients before and 40 to 60 days and 9 months after surgery. Presurgery diagnoses included benign (Graves disease, nodular toxic goiter, nodular nontoxic goiter) and malignant (differentiated thyroid cancer) conditions.

Results: Mean preintervention weight of the entire study group significantly increased (P

Conclusion: Thyroidectomy is associated with a significant increase in body weight, which is not limited to patients with Graves disease. Postsurgery TSH levels do not account for subsequent body-weight changes. Short-term changes (40 to 60 days postsurgery) in body weight are highly predictive of the outcome at 9 months, suggesting that early factors related to thyroidectomy per se might play a role.

Original languageEnglish
Pages (from-to)1151-1158
Number of pages8
JournalEndocrine Practice
Volume20
Issue number11
DOIs
Publication statusPublished - Nov 1 2014

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

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