BOLD response to spatial phase congruency in human brain

Andrea Perna, Michela Tosetti, Domenico Montanaro, Maria Concetta Morrone

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Human psychophysical observations, computational models, and the selectivity of neurons in primary visual cortex all suggest that an early step in visual processing is the detection of features such as lines and edges. However, previous fMRI experiments investigating the responses of early visual areas to phase coherence have led to apparently discordant results. We studied the human brain BOLD responses to structured periodic band-pass images of matched amplitude spectrum but of different phase spectra, arranged to create three distinct types of stimuli: pure edges; pure lines (matched global and local energy to the edges, but different phase); and random noise (random phase spectrum, hence no salient features, and a different spatial distribution of local energy from the lines and edges stimuli). Alternation of lines against edges did not activate primary visual cortex, but did activate two higher order visual areas. Alternation of these lines or edges against the random stimulus produced a strong activity in many visual areas, including primary visual cortex. Interestingly, the BOLD activity was higher for the edges and lines than for the random stimuli for a wide range of stimulus contrasts, indicating the presence of non-linear gain modulation in the cell response. These results show that phase congruency is coded at the level of primary visual cortex. We show that a stage of response gain modulation can explain our present and previous fMRI discordant results.

Original languageEnglish
Article number15
JournalJournal of Vision
Volume8
Issue number10
DOIs
Publication statusPublished - Dec 22 2008

Fingerprint

Visual Cortex
Brain
Magnetic Resonance Imaging
Neurons

Keywords

  • Contrast gain
  • Functional imaging
  • Receptive fields
  • Shape and contour
  • Spatial vision
  • Visual cortex

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

Cite this

BOLD response to spatial phase congruency in human brain. / Perna, Andrea; Tosetti, Michela; Montanaro, Domenico; Morrone, Maria Concetta.

In: Journal of Vision, Vol. 8, No. 10, 15, 22.12.2008.

Research output: Contribution to journalArticle

@article{66893ddcf714449ab1d07a9107fd74fd,
title = "BOLD response to spatial phase congruency in human brain",
abstract = "Human psychophysical observations, computational models, and the selectivity of neurons in primary visual cortex all suggest that an early step in visual processing is the detection of features such as lines and edges. However, previous fMRI experiments investigating the responses of early visual areas to phase coherence have led to apparently discordant results. We studied the human brain BOLD responses to structured periodic band-pass images of matched amplitude spectrum but of different phase spectra, arranged to create three distinct types of stimuli: pure edges; pure lines (matched global and local energy to the edges, but different phase); and random noise (random phase spectrum, hence no salient features, and a different spatial distribution of local energy from the lines and edges stimuli). Alternation of lines against edges did not activate primary visual cortex, but did activate two higher order visual areas. Alternation of these lines or edges against the random stimulus produced a strong activity in many visual areas, including primary visual cortex. Interestingly, the BOLD activity was higher for the edges and lines than for the random stimuli for a wide range of stimulus contrasts, indicating the presence of non-linear gain modulation in the cell response. These results show that phase congruency is coded at the level of primary visual cortex. We show that a stage of response gain modulation can explain our present and previous fMRI discordant results.",
keywords = "Contrast gain, Functional imaging, Receptive fields, Shape and contour, Spatial vision, Visual cortex",
author = "Andrea Perna and Michela Tosetti and Domenico Montanaro and Morrone, {Maria Concetta}",
year = "2008",
month = "12",
day = "22",
doi = "10.1167/8.10.15",
language = "English",
volume = "8",
journal = "Journal of Vision",
issn = "1534-7362",
publisher = "Association for Research in Vision and Ophthalmology Inc.",
number = "10",

}

TY - JOUR

T1 - BOLD response to spatial phase congruency in human brain

AU - Perna, Andrea

AU - Tosetti, Michela

AU - Montanaro, Domenico

AU - Morrone, Maria Concetta

PY - 2008/12/22

Y1 - 2008/12/22

N2 - Human psychophysical observations, computational models, and the selectivity of neurons in primary visual cortex all suggest that an early step in visual processing is the detection of features such as lines and edges. However, previous fMRI experiments investigating the responses of early visual areas to phase coherence have led to apparently discordant results. We studied the human brain BOLD responses to structured periodic band-pass images of matched amplitude spectrum but of different phase spectra, arranged to create three distinct types of stimuli: pure edges; pure lines (matched global and local energy to the edges, but different phase); and random noise (random phase spectrum, hence no salient features, and a different spatial distribution of local energy from the lines and edges stimuli). Alternation of lines against edges did not activate primary visual cortex, but did activate two higher order visual areas. Alternation of these lines or edges against the random stimulus produced a strong activity in many visual areas, including primary visual cortex. Interestingly, the BOLD activity was higher for the edges and lines than for the random stimuli for a wide range of stimulus contrasts, indicating the presence of non-linear gain modulation in the cell response. These results show that phase congruency is coded at the level of primary visual cortex. We show that a stage of response gain modulation can explain our present and previous fMRI discordant results.

AB - Human psychophysical observations, computational models, and the selectivity of neurons in primary visual cortex all suggest that an early step in visual processing is the detection of features such as lines and edges. However, previous fMRI experiments investigating the responses of early visual areas to phase coherence have led to apparently discordant results. We studied the human brain BOLD responses to structured periodic band-pass images of matched amplitude spectrum but of different phase spectra, arranged to create three distinct types of stimuli: pure edges; pure lines (matched global and local energy to the edges, but different phase); and random noise (random phase spectrum, hence no salient features, and a different spatial distribution of local energy from the lines and edges stimuli). Alternation of lines against edges did not activate primary visual cortex, but did activate two higher order visual areas. Alternation of these lines or edges against the random stimulus produced a strong activity in many visual areas, including primary visual cortex. Interestingly, the BOLD activity was higher for the edges and lines than for the random stimuli for a wide range of stimulus contrasts, indicating the presence of non-linear gain modulation in the cell response. These results show that phase congruency is coded at the level of primary visual cortex. We show that a stage of response gain modulation can explain our present and previous fMRI discordant results.

KW - Contrast gain

KW - Functional imaging

KW - Receptive fields

KW - Shape and contour

KW - Spatial vision

KW - Visual cortex

UR - http://www.scopus.com/inward/record.url?scp=58149481945&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=58149481945&partnerID=8YFLogxK

U2 - 10.1167/8.10.15

DO - 10.1167/8.10.15

M3 - Article

VL - 8

JO - Journal of Vision

JF - Journal of Vision

SN - 1534-7362

IS - 10

M1 - 15

ER -