Bolus feeding has no effect on cerebral hemodynamics, irrespective of gestational age

Stefano Bembich, Gabriele Cont, Jenny Bua, Chiara Orlando, Donatella Di Benedetto, Sergio Demarini

Research output: Contribution to journalArticlepeer-review


OBJECTIVE: By multichannel near-infrared spectroscopy, we studied if gestational age has any influence on preterm cerebral hemodynamics, during bolus feeding.

METHODS: Oxy-haemoglobin (HbO2), as cerebral blood flow estimate, and the ratio between HbO2and total haemoglobin (HbO2/HbTot), as cerebral oxygenation estimate, were assessed in 40 stable premature infants, during a 10 min bolus feeding.

RESULTS: We found no effect of any of the gestational ages studied (25-34 weeks) either on cerebral blood flow or on oxygenation, during a bolus feeding procedure.

CONCLUSIONS: Bolus feeding appears not to affect cerebral hemodynamics of uncritically preterm infants, irrespective of gestational age.

Original languageEnglish
Pages (from-to)1029-1031
Number of pages3
JournalJournal of Maternal-Fetal and Neonatal Medicine
Issue number9
Publication statusPublished - May 2017


  • Cerebrovascular Circulation/physiology
  • Enteral Nutrition/adverse effects
  • Female
  • Gestational Age
  • Heart Rate/physiology
  • Humans
  • Infant, Newborn
  • Infant, Premature/blood
  • Intensive Care Units, Neonatal
  • Male
  • Oxygen/blood
  • Oxyhemoglobins/analysis
  • Spectroscopy, Near-Infrared/methods


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