Bone marrow evaluation in small cell carcinoma of the lung

G. Giaccone, L. Ciuffreda, M. Donadio, P. Ferrati, M. Risio, G. Leria, G. Bonardi, A. Calciati

Research output: Contribution to journalArticle

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Abstract

Bone marrow examination is commonly included in the staging of small cell lung carcinoma (SCLC). We reviewed marrow samples of 103 patients. Marrow examination was mainly performed by unilateral or bilateral biopsy of iliac crests, using a Jamshidi needle. Only 6 of 97 evaluable cases (6.2 per cent) were positive for marrow metastases at staging, and in 3 cases (3 per cent) bone marrow was the only metastatic site. No focal metastases were found in additional sections made from the blocks of negative samples. In our experience bone marrow biopsy was of little value in staging SCLC. Bilateral biopsy plus aspirate, with the addition of more sophisticated staining techniques might, however, provide a higher yield of positive marrow involvement.

Original languageEnglish
Pages (from-to)185-188
Number of pages4
JournalActa Oncologica
Volume26
Issue number3
DOIs
Publication statusPublished - 1987

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Small Cell Lung Carcinoma
Bone Marrow
Biopsy
Neoplasm Metastasis
Bone Marrow Examination
Needles
Staining and Labeling

Keywords

  • Bone marrow biopsy
  • Lung neoplasms
  • Small cell carcinoma

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Hematology

Cite this

Giaccone, G., Ciuffreda, L., Donadio, M., Ferrati, P., Risio, M., Leria, G., ... Calciati, A. (1987). Bone marrow evaluation in small cell carcinoma of the lung. Acta Oncologica, 26(3), 185-188. https://doi.org/10.3109/02841868709091428

Bone marrow evaluation in small cell carcinoma of the lung. / Giaccone, G.; Ciuffreda, L.; Donadio, M.; Ferrati, P.; Risio, M.; Leria, G.; Bonardi, G.; Calciati, A.

In: Acta Oncologica, Vol. 26, No. 3, 1987, p. 185-188.

Research output: Contribution to journalArticle

Giaccone, G, Ciuffreda, L, Donadio, M, Ferrati, P, Risio, M, Leria, G, Bonardi, G & Calciati, A 1987, 'Bone marrow evaluation in small cell carcinoma of the lung', Acta Oncologica, vol. 26, no. 3, pp. 185-188. https://doi.org/10.3109/02841868709091428
Giaccone G, Ciuffreda L, Donadio M, Ferrati P, Risio M, Leria G et al. Bone marrow evaluation in small cell carcinoma of the lung. Acta Oncologica. 1987;26(3):185-188. https://doi.org/10.3109/02841868709091428
Giaccone, G. ; Ciuffreda, L. ; Donadio, M. ; Ferrati, P. ; Risio, M. ; Leria, G. ; Bonardi, G. ; Calciati, A. / Bone marrow evaluation in small cell carcinoma of the lung. In: Acta Oncologica. 1987 ; Vol. 26, No. 3. pp. 185-188.
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