TY - JOUR
T1 - Bone mass status in different degrees of chronic renal failure
AU - Bianchi, M. L.
AU - Colantonio, G.
AU - Montesano, A.
AU - Trevisan, C.
AU - Ortolani, S.
AU - Rossi, R.
AU - Buccianti, G.
PY - 1992
Y1 - 1992
N2 - Bone mineral density (BMD) was evaluated in 69 patients with chronic renal failure (CRF) and in healthy controls matched for age, sex, and, for women, menopausal status. Both appendicular (predominantly cortical) and axial (predominantly trabecular) bone mass were measured. Appendicular BMD was measured by single photon absorptiometry on the distal forearm and axial BMD was measured by dual photon absorptiometry on the lumbar spine. Patients were divided into three groups on the basis of creatinine clearance: group 1, 58 to 36 ml/min; group 2,30 to 18 ml/mm; group 3, 15 to 9 ml/min. Both appendicular and axial BMD decreased with the worsening of renal failure. Parathyroid hormone levels were inversely correlated with the values of appendicular BMD. BMD values were significantly lower in post-menopausal than in premenopausal women. Months of menopause were inversely correlated with axial BMD values. Appendicular BMD was lower in CRF patients than in controls, and both appendicular and axial BMD were significantly lower in postmenopausal uremic women than in post-menopausal healthy women.
AB - Bone mineral density (BMD) was evaluated in 69 patients with chronic renal failure (CRF) and in healthy controls matched for age, sex, and, for women, menopausal status. Both appendicular (predominantly cortical) and axial (predominantly trabecular) bone mass were measured. Appendicular BMD was measured by single photon absorptiometry on the distal forearm and axial BMD was measured by dual photon absorptiometry on the lumbar spine. Patients were divided into three groups on the basis of creatinine clearance: group 1, 58 to 36 ml/min; group 2,30 to 18 ml/mm; group 3, 15 to 9 ml/min. Both appendicular and axial BMD decreased with the worsening of renal failure. Parathyroid hormone levels were inversely correlated with the values of appendicular BMD. BMD values were significantly lower in post-menopausal than in premenopausal women. Months of menopause were inversely correlated with axial BMD values. Appendicular BMD was lower in CRF patients than in controls, and both appendicular and axial BMD were significantly lower in postmenopausal uremic women than in post-menopausal healthy women.
KW - Bone mineral density
KW - Chronic renal failure
KW - Single and dual photon absorptiometry
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U2 - 10.1016/8756-3282(92)90201-7
DO - 10.1016/8756-3282(92)90201-7
M3 - Article
C2 - 1637568
AN - SCOPUS:0026691176
VL - 13
SP - 225
EP - 228
JO - Bone
JF - Bone
SN - 8756-3282
IS - 3
ER -