Bone regeneration and stem cells

K. Arvidson, B. M. Abdallah, L. A. Applegate, N. Baldini, E. Cenni, E. Gomez-Barrena, D. Granchi, M. Kassem, Y. T. Konttinen, K. Mustafa, D. P. Pioletti, T. Sillat, A. Finne-Wistrand

Research output: Contribution to journalArticle

Abstract

This invited review covers research areas of central importance for orthopaedic and maxillofacial bone tissue repair, including normal fracture healing and healing problems, biomaterial scaffolds for tissue engineering, mesenchymal and foetal stem cells, effects of sex steroids on mesenchymal stem cells, use of platelet-rich plasma for tissue repair, osteogenesis and its molecular markers. A variety of cells in addition to stem cells, as well as advances in materials science to meet specific requirements for bone and soft tissue regeneration by addition of bioactive molecules, are discussed.

Original languageEnglish
Pages (from-to)718-746
Number of pages29
JournalJournal of Cellular and Molecular Medicine
Volume15
Issue number4
DOIs
Publication statusPublished - Apr 2011

Keywords

  • Biomaterials
  • Bone regeneration
  • Polymers
  • Regenerative medicine
  • Stem cells

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Medicine

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  • Cite this

    Arvidson, K., Abdallah, B. M., Applegate, L. A., Baldini, N., Cenni, E., Gomez-Barrena, E., Granchi, D., Kassem, M., Konttinen, Y. T., Mustafa, K., Pioletti, D. P., Sillat, T., & Finne-Wistrand, A. (2011). Bone regeneration and stem cells. Journal of Cellular and Molecular Medicine, 15(4), 718-746. https://doi.org/10.1111/j.1582-4934.2010.01224.x