Bordetella bronchiseptica pneumonia in a patient with lung cancer; a case report of a rare infection

Manlio Monti, Danila Diano, Francesco Allegrini, Angelo Delmonte, Valentina Fausti, Paola Cravero, Giulia Marcantognini, Giovanni Luca Frassineti

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Bordetella bronchiseptica (B.bronchiseptica) is a frequent cause of respiratory infections in animals but rarely causes serious infection in humans. We present a rare case of B. bronchiseptica pneumonia in a patient with lung cancer. Case presentation: A 52-year-old white male with non small cell lung cancer developed fever during treatment with nivolumab. A persistent productive cough and a deterioration in his clinical condition led to his hospitalization for evaluation. Bronchoscopy was performed and a diagnosis of B. bronchiseptica pneumonia was made. The infection was successfully managed by antiobiotic therapy. Conclusions:B. bronchiseptica is a pathogen that can cause serious infection in humans, especially in immunocompromised or immunoincompetent individuals. In our patient it showed unusual resistance to cephalosporins and poor sensitivity to amikacin. To our knowledge this is the first case of such an infection in a lung cancer patient undergoing treatment with nivolumab. When B. bronchiseptica is identified, the possibility of a nosocomial transmission must be considered.

Original languageEnglish
Article number644
JournalBMC Infectious Diseases
Volume17
Issue number1
DOIs
Publication statusPublished - Sep 25 2017

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Bordetella bronchiseptica
Lung Neoplasms
Pneumonia
Infection
Cephalosporin Resistance
Amikacin
Bronchoscopy
Cough
Non-Small Cell Lung Carcinoma
Respiratory Tract Infections
Hospitalization
Fever
Therapeutics

Keywords

  • Bordetella bronchiseptica
  • Cavitary lung lesion
  • Nivolumab
  • Nosocomial infection
  • Rare infection

ASJC Scopus subject areas

  • Infectious Diseases

Cite this

Bordetella bronchiseptica pneumonia in a patient with lung cancer; a case report of a rare infection. / Monti, Manlio; Diano, Danila; Allegrini, Francesco; Delmonte, Angelo; Fausti, Valentina; Cravero, Paola; Marcantognini, Giulia; Frassineti, Giovanni Luca.

In: BMC Infectious Diseases, Vol. 17, No. 1, 644, 25.09.2017.

Research output: Contribution to journalArticle

Monti, Manlio ; Diano, Danila ; Allegrini, Francesco ; Delmonte, Angelo ; Fausti, Valentina ; Cravero, Paola ; Marcantognini, Giulia ; Frassineti, Giovanni Luca. / Bordetella bronchiseptica pneumonia in a patient with lung cancer; a case report of a rare infection. In: BMC Infectious Diseases. 2017 ; Vol. 17, No. 1.
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