TY - JOUR
T1 - Borrelia burgdorferi infection and Lyme disease in children
AU - Esposito, Susanna
AU - Bosis, Samantha
AU - Sabatini, Caterina
AU - Tagliaferri, Laura
AU - Principi, Nicola
PY - 2013/3
Y1 - 2013/3
N2 - Lyme disease is a multisystem disease that frequently affects children. It is caused by a group of related spirochetes, Borrelia burgdorferi sensu lato, that are transmitted by ticks belonging to species of the genus Ixodes. The clinical characteristics of Lyme disease in pediatrics resemble those observed in adults, although the symptoms may last for a shorter time and the outcome may be better. However, identifying Lyme disease in children can be significantly more difficult because some of its signs and symptoms can be similar to those of other common pediatric clinical manifestations. Finally, the diagnostic and therapeutic approach to childhood Lyme disease is frequently not codified, and guidelines specifically prepared for adults are used for children without having been validated. This review of the currently available data will evaluate what may be the best approach to the diagnosis and treatment of B. burgdorferi infection and disease in the pediatric population.
AB - Lyme disease is a multisystem disease that frequently affects children. It is caused by a group of related spirochetes, Borrelia burgdorferi sensu lato, that are transmitted by ticks belonging to species of the genus Ixodes. The clinical characteristics of Lyme disease in pediatrics resemble those observed in adults, although the symptoms may last for a shorter time and the outcome may be better. However, identifying Lyme disease in children can be significantly more difficult because some of its signs and symptoms can be similar to those of other common pediatric clinical manifestations. Finally, the diagnostic and therapeutic approach to childhood Lyme disease is frequently not codified, and guidelines specifically prepared for adults are used for children without having been validated. This review of the currently available data will evaluate what may be the best approach to the diagnosis and treatment of B. burgdorferi infection and disease in the pediatric population.
KW - Borrelia burgdorferi
KW - Erythema migrans
KW - Heart borreliosis
KW - Lyme arthritis
KW - Lyme disease
KW - Lyme meningitis
KW - Neuroborreliosis
UR - http://www.scopus.com/inward/record.url?scp=84874486494&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84874486494&partnerID=8YFLogxK
U2 - 10.1016/j.ijid.2012.09.014
DO - 10.1016/j.ijid.2012.09.014
M3 - Article
C2 - 23141587
AN - SCOPUS:84874486494
VL - 17
JO - International Journal of Infectious Diseases
JF - International Journal of Infectious Diseases
SN - 1201-9712
IS - 3
ER -