Botulinum toxin as a treatment for blepharospasm, spasmodic torticollis and hemifacial spasm

A. Albanese, C. Colosimo, D. Carretta, A. Dickmann, A. R. Bentivoglio, P. Tonali

Research output: Contribution to journalArticlepeer-review

Abstract

Fifty-two patients affected by focal dystonia or hemifacial spasm were treated with repeated injections of botulinum toxin. A clinical improvement was observed in all patients with blepharospasm; clinical benefit had a mean duration of 10 weeks. Clinical results were less impressive, but also favourable in patients affected by spasmodic torticollis and by hemifacial spasm. In the latter, the incidence of drug-induced paresis was much higher than that observed in patients with blepharospasm, even though the doses of toxin injected were significantly lower.

Original languageEnglish
Pages (from-to)112-117
Number of pages6
JournalEuropean Neurology
Volume32
Issue number2
Publication statusPublished - 1992

Keywords

  • Blepharospasm
  • Botulinum toxin
  • Dystonia
  • Hemifacial spasm
  • Torticollis

ASJC Scopus subject areas

  • Clinical Neurology

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