Botulinum toxin for chronic migraine: Clinical trials and technical aspects

Cristina Tassorelli, Grazia Sances, Micol Avenali, Roberto De Icco, Daniele Martinelli, Vito Bitetto, Giuseppe Nappi, Giorgio Sandrini

Research output: Contribution to journalArticlepeer-review


OnabotulinumtoxinA has been approved for the prophylaxis of chronic migraine following the demonstration of efficacy in two large controlled trials. Data collected from pragmatic studies in the real-life setting have contributed important additional information useful for the management of this group of extremely disabled and challenging patients. The main findings from these studies are presented and discussed.

Original languageEnglish
Pages (from-to)111-115
Number of pages5
Publication statusPublished - Jun 1 2018


  • Exploratory studies
  • Injection paradigm
  • Migraine
  • Real-life studies
  • Technical issues

ASJC Scopus subject areas

  • Toxicology


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