Botulinum toxin in the treatment of chronic constipation in Parkinson's disease

A. Albanese, G. Maria, A. R. Bentivoglio, G. Brisinda, E. Cassetta, P. Tonali

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Constipation and defaecatory dysfunction occur approximately five times more frequently in patients with Parkinson's disease than in those without. Ineffective defaecation in Parkinson's disease has been correlated with failure of relaxation or with paradoxical contraction of the puborectalis muscle during straining. This contraction has been treated by surgical division of the muscle, a therapy that has often been unsuccessful and is accompanied by a prohibitively high rate of incontinence. We investigated the efficacy of botulinum toxin A injections in treating Parkinsonian patients with severe constipation due to outlet obstruction (puborectalis syndrome).

Original languageEnglish
JournalEuropean Journal of Neurology
Volume4
Issue numberSUPPL.2
Publication statusPublished - 1997

Fingerprint

Botulinum Toxins
Constipation
Parkinson Disease
Type A Botulinum Toxins
Defecation
Muscle Contraction
Muscles
Injections
Therapeutics

Keywords

  • Botulinum toxin
  • Constipation
  • Parkinson's disease
  • Puborectalis muscle

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Albanese, A., Maria, G., Bentivoglio, A. R., Brisinda, G., Cassetta, E., & Tonali, P. (1997). Botulinum toxin in the treatment of chronic constipation in Parkinson's disease. European Journal of Neurology, 4(SUPPL.2).

Botulinum toxin in the treatment of chronic constipation in Parkinson's disease. / Albanese, A.; Maria, G.; Bentivoglio, A. R.; Brisinda, G.; Cassetta, E.; Tonali, P.

In: European Journal of Neurology, Vol. 4, No. SUPPL.2, 1997.

Research output: Contribution to journalArticle

Albanese, A, Maria, G, Bentivoglio, AR, Brisinda, G, Cassetta, E & Tonali, P 1997, 'Botulinum toxin in the treatment of chronic constipation in Parkinson's disease', European Journal of Neurology, vol. 4, no. SUPPL.2.
Albanese A, Maria G, Bentivoglio AR, Brisinda G, Cassetta E, Tonali P. Botulinum toxin in the treatment of chronic constipation in Parkinson's disease. European Journal of Neurology. 1997;4(SUPPL.2).
Albanese, A. ; Maria, G. ; Bentivoglio, A. R. ; Brisinda, G. ; Cassetta, E. ; Tonali, P. / Botulinum toxin in the treatment of chronic constipation in Parkinson's disease. In: European Journal of Neurology. 1997 ; Vol. 4, No. SUPPL.2.
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AU - Tonali, P.

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