Bovine papillomavirus type 4 in oesophageal papillomas of cattle from the south of Italy

G. Borzacchiello, V. Ambrosio, S. Roperto, F. Poggiali, E. Tsirimonakis, A. Venuti, M. S. Campo, F. Roperto

Research output: Contribution to journalArticle

Abstract

Oesophageal papillomas are known to occur in cattle infected with bovine papillomavirus type 4 (BPV-4), and BPV-4 papillomas may undergo malignant progression in cattle that feed on bracken fern. In the south of Italy, where bracken fern is common, examination of 1133 slaughterhouse cattle aged 4-12 years revealed oesophageal lesions (single or multiple peduncuolated proliferations, or mucosal thickening) in 147 (13%). These two types of lesion were consistent with exophytic and inverted papilloma, respectively. BPV-4 was detected by polymerase chain reaction (PCR) analysis in >60% of the samples in which oesophageal papilloma was diagnosed histopathologically. Nucleotide sequencing of the PCR amplicons confirmed the presence of BPV-4 in the papillomas. This is the first report of such infections in a European country other than Britain.

Original languageEnglish
Pages (from-to)203-206
Number of pages4
JournalJournal of Comparative Pathology
Volume128
Issue number2-3
DOIs
Publication statusPublished - Feb 2003

ASJC Scopus subject areas

  • Animal Science and Zoology

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    Borzacchiello, G., Ambrosio, V., Roperto, S., Poggiali, F., Tsirimonakis, E., Venuti, A., Campo, M. S., & Roperto, F. (2003). Bovine papillomavirus type 4 in oesophageal papillomas of cattle from the south of Italy. Journal of Comparative Pathology, 128(2-3), 203-206. https://doi.org/10.1053/jcpa.2002.0626