BrachyView

Multiple seed position reconstruction and comparison with CT post-implant dosimetry

S. Alnaghy, K. J. Loo, D. L. Cutajar, M. Jalayer, C. Tenconi, M. Favoino, R. Rietti, M. Tartaglia, F. Carriero, M. Safavi-Naeini, J. Bucci, J. Jakubek, S. Pospisil, M. Zaider, M. L F Lerch, A. B. Rosenfeld, Marco Petasecca

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

BrachyView is a novel in-body imaging system utilising high-resolution pixelated silicon detectors (Timepix) and a pinhole collimator for brachytherapy source localisation. Recent studies have investigated various options for real-time intraoperative dynamic dose treatment planning to increase the quality of implants. In a previous proof-of-concept study, the justification of the pinhole concept was shown, allowing for the next step whereby multiple active seeds are implanted into a PMMA phantom to simulate a more realistic clinical scenario. In this study, 20 seeds were implanted and imaged using a lead pinhole of 400 μ m diameter. BrachyView was able to resolve the seed positions within 1-2 mm of expected positions, which was verified by co-registering with a full clinical post-implant CT scan.

Original languageEnglish
Article numberP05002
JournalJournal of Instrumentation
Volume11
Issue number5
DOIs
Publication statusPublished - May 3 2016

Fingerprint

Implant
pinholes
Dosimetry
dosimeters
Seed
seeds
Source Localization
Phantom
Imaging System
Justification
Dose
Resolve
Silicon detectors
Silicon
High Resolution
Computerized tomography
Detector
Planning
collimators
Real-time

Keywords

  • Dosimetry concepts and apparatus
  • Instrumentation for gammaelectron therapy
  • Intra-operative probes
  • X-ray detectors

ASJC Scopus subject areas

  • Instrumentation
  • Mathematical Physics

Cite this

Alnaghy, S., Loo, K. J., Cutajar, D. L., Jalayer, M., Tenconi, C., Favoino, M., ... Petasecca, M. (2016). BrachyView: Multiple seed position reconstruction and comparison with CT post-implant dosimetry. Journal of Instrumentation, 11(5), [P05002]. https://doi.org/10.1088/1748-0221/11/05/P05002

BrachyView : Multiple seed position reconstruction and comparison with CT post-implant dosimetry. / Alnaghy, S.; Loo, K. J.; Cutajar, D. L.; Jalayer, M.; Tenconi, C.; Favoino, M.; Rietti, R.; Tartaglia, M.; Carriero, F.; Safavi-Naeini, M.; Bucci, J.; Jakubek, J.; Pospisil, S.; Zaider, M.; Lerch, M. L F; Rosenfeld, A. B.; Petasecca, Marco.

In: Journal of Instrumentation, Vol. 11, No. 5, P05002, 03.05.2016.

Research output: Contribution to journalArticle

Alnaghy, S, Loo, KJ, Cutajar, DL, Jalayer, M, Tenconi, C, Favoino, M, Rietti, R, Tartaglia, M, Carriero, F, Safavi-Naeini, M, Bucci, J, Jakubek, J, Pospisil, S, Zaider, M, Lerch, MLF, Rosenfeld, AB & Petasecca, M 2016, 'BrachyView: Multiple seed position reconstruction and comparison with CT post-implant dosimetry', Journal of Instrumentation, vol. 11, no. 5, P05002. https://doi.org/10.1088/1748-0221/11/05/P05002
Alnaghy, S. ; Loo, K. J. ; Cutajar, D. L. ; Jalayer, M. ; Tenconi, C. ; Favoino, M. ; Rietti, R. ; Tartaglia, M. ; Carriero, F. ; Safavi-Naeini, M. ; Bucci, J. ; Jakubek, J. ; Pospisil, S. ; Zaider, M. ; Lerch, M. L F ; Rosenfeld, A. B. ; Petasecca, Marco. / BrachyView : Multiple seed position reconstruction and comparison with CT post-implant dosimetry. In: Journal of Instrumentation. 2016 ; Vol. 11, No. 5.
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