BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis

C. Cremolini, M. Di Bartolomeo, A. Amatu, C. Antoniotti, R. Moretto, R. Berenato, F. Perrone, E. Tamborini, G. Aprile, S. Lonardi, A. Sartore-Bianchi, G. Fontanini, M. Milione, C. Lauricella, S. Siena, A. Falcone, F. De Braud, F. Loupakis, Filippo Pietrantonio

Research output: Contribution to journalArticle

Abstract

Background: While the negative prognostic role of BRAF V600E mutation in metastatic colorectal cancer (mCRC) is well established, the impact of BRAF codons 594 and 596 mutations, occurring in

Original languageEnglish
Article numbermdv290
Pages (from-to)2092-2097
Number of pages6
JournalAnnals of Oncology
Volume26
Issue number10
DOIs
Publication statusPublished - Oct 1 2015

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Keywords

  • BRAF
  • Codons 594 and 596
  • Colorectal cancer
  • Prognosis

ASJC Scopus subject areas

  • Oncology
  • Hematology

Cite this

Cremolini, C., Di Bartolomeo, M., Amatu, A., Antoniotti, C., Moretto, R., Berenato, R., Perrone, F., Tamborini, E., Aprile, G., Lonardi, S., Sartore-Bianchi, A., Fontanini, G., Milione, M., Lauricella, C., Siena, S., Falcone, A., De Braud, F., Loupakis, F., & Pietrantonio, F. (2015). BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis. Annals of Oncology, 26(10), 2092-2097. [mdv290]. https://doi.org/10.1093/annonc/mdv290