BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis

C. Cremolini; M. Di Bartolomeo; A. Amatu; C. Antoniotti; R. Moretto; R. Berenato; F. Perrone; E. Tamborini; G. Aprile; S. Lonardi; A. Sartore-Bianchi; G. Fontanini; M. Milione; C. Lauricella; S. Siena; A. Falcone; F. De Braud; F. Loupakis; Filippo Pietrantonio

doi:10.1093/annonc/mdv290

BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis

C. Cremolini, M. Di Bartolomeo, A. Amatu, C. Antoniotti, R. Moretto, R. Berenato, F. Perrone, E. Tamborini, G. Aprile, S. Lonardi, A. Sartore-Bianchi, G. Fontanini, M. Milione, C. Lauricella, S. Siena, A. Falcone, F. De Braud, F. Loupakis, Filippo Pietrantonio

Research output: Contribution to journal › Article › peer-review

Abstract

Background: While the negative prognostic role of BRAF V600E mutation in metastatic colorectal cancer (mCRC) is well established, the impact of BRAF codons 594 and 596 mutations, occurring in

Original language	English
Article number	mdv290
Pages (from-to)	2092-2097
Number of pages	6
Journal	Annals of Oncology
Volume	26
Issue number	10
DOIs	https://doi.org/10.1093/annonc/mdv290
Publication status	Published - Oct 1 2015

Keywords

BRAF
Codons 594 and 596
Colorectal cancer
Prognosis

ASJC Scopus subject areas

Oncology
Hematology

Access to Document

10.1093/annonc/mdv290

Fingerprint Dive into the research topics of 'BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis'. Together they form a unique fingerprint.

Cite this

Cremolini, C., Di Bartolomeo, M., Amatu, A., Antoniotti, C., Moretto, R., Berenato, R., Perrone, F., Tamborini, E., Aprile, G., Lonardi, S., Sartore-Bianchi, A., Fontanini, G., Milione, M., Lauricella, C., Siena, S., Falcone, A., De Braud, F., Loupakis, F., & Pietrantonio, F. (2015). BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis. Annals of Oncology, 26(10), 2092-2097. [mdv290]. https://doi.org/10.1093/annonc/mdv290

BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis. / Cremolini, C.; Di Bartolomeo, M.; Amatu, A.; Antoniotti, C.; Moretto, R.; Berenato, R.; Perrone, F.; Tamborini, E.; Aprile, G.; Lonardi, S.; Sartore-Bianchi, A.; Fontanini, G.; Milione, M.; Lauricella, C.; Siena, S.; Falcone, A.; De Braud, F.; Loupakis, F.; Pietrantonio, Filippo.

In: Annals of Oncology, Vol. 26, No. 10, mdv290, 01.10.2015, p. 2092-2097.

Research output: Contribution to journal › Article › peer-review

Cremolini, C, Di Bartolomeo, M, Amatu, A, Antoniotti, C, Moretto, R, Berenato, R, Perrone, F , Tamborini, E, Aprile, G, Lonardi, S, Sartore-Bianchi, A, Fontanini, G, Milione, M, Lauricella, C, Siena, S, Falcone, A, De Braud, F, Loupakis, F & Pietrantonio, F 2015, 'BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis', Annals of Oncology, vol. 26, no. 10, mdv290, pp. 2092-2097. https://doi.org/10.1093/annonc/mdv290

Cremolini, C. ; Di Bartolomeo, M. ; Amatu, A. ; Antoniotti, C. ; Moretto, R. ; Berenato, R. ; Perrone, F. ; Tamborini, E. ; Aprile, G. ; Lonardi, S. ; Sartore-Bianchi, A. ; Fontanini, G. ; Milione, M. ; Lauricella, C. ; Siena, S. ; Falcone, A. ; De Braud, F. ; Loupakis, F. ; Pietrantonio, Filippo. / BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis. In: Annals of Oncology. 2015 ; Vol. 26, No. 10. pp. 2092-2097.

@article{5e72d33ac5a142f18e4b052c3f6849de,

title = "BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis",

abstract = "Background: While the negative prognostic role of BRAF V600E mutation in metastatic colorectal cancer (mCRC) is well established, the impact of BRAF codons 594 and 596 mutations, occurring in ",

keywords = "BRAF, Codons 594 and 596, Colorectal cancer, Prognosis",

author = "C. Cremolini and {Di Bartolomeo}, M. and A. Amatu and C. Antoniotti and R. Moretto and R. Berenato and F. Perrone and E. Tamborini and G. Aprile and S. Lonardi and A. Sartore-Bianchi and G. Fontanini and M. Milione and C. Lauricella and S. Siena and A. Falcone and {De Braud}, F. and F. Loupakis and Filippo Pietrantonio",

year = "2015",

month = oct,

day = "1",

doi = "10.1093/annonc/mdv290",

language = "English",

volume = "26",

pages = "2092--2097",

journal = "Annals of Oncology",

issn = "0923-7534",

publisher = "NLM (Medline)",

number = "10",

}

TY - JOUR

T1 - BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis

AU - Cremolini, C.

AU - Di Bartolomeo, M.

AU - Amatu, A.

AU - Antoniotti, C.

AU - Moretto, R.

AU - Berenato, R.

AU - Perrone, F.

AU - Tamborini, E.

AU - Aprile, G.

AU - Lonardi, S.

AU - Sartore-Bianchi, A.

AU - Fontanini, G.

AU - Milione, M.

AU - Lauricella, C.

AU - Siena, S.

AU - Falcone, A.

AU - De Braud, F.

AU - Loupakis, F.

AU - Pietrantonio, Filippo

PY - 2015/10/1

Y1 - 2015/10/1

N2 - Background: While the negative prognostic role of BRAF V600E mutation in metastatic colorectal cancer (mCRC) is well established, the impact of BRAF codons 594 and 596 mutations, occurring in

AB - Background: While the negative prognostic role of BRAF V600E mutation in metastatic colorectal cancer (mCRC) is well established, the impact of BRAF codons 594 and 596 mutations, occurring in

KW - BRAF

KW - Codons 594 and 596

KW - Colorectal cancer

KW - Prognosis

UR - http://www.scopus.com/inward/record.url?scp=84943799055&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84943799055&partnerID=8YFLogxK

U2 - 10.1093/annonc/mdv290

DO - 10.1093/annonc/mdv290

M3 - Article

C2 - 26153495

AN - SCOPUS:84943799055

VL - 26

SP - 2092

EP - 2097

JO - Annals of Oncology

JF - Annals of Oncology

SN - 0923-7534

IS - 10

M1 - mdv290

ER -

BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this