Brain-computer interface and semantic classical conditioning of communication in paralysis

Daniele De Massari, Tamara Matuz, Adrian Furdea, Carolin A. Ruf, Sebastian Halder, Niels Birbaumer

Research output: Contribution to journalArticle

Abstract

We propose a classical semantic conditioning procedure to allow basic yes-no communication in the completely locked-in state as an alternative to instrumental-operant learning of brain responses, which is the common approach in brain-computer interface research. More precisely, it was intended to establish cortical responses to the trueness of a statement irrespective of the particular constituent words and letters or sounds of the words. As unconditioned stimulus short aversive stimuli consisting of 1-ms electrical pulses were used. True and false statements were presented acoustically and only the true statements were immediately followed by electrical stimuli.15 healthy participants and one locked-in ALS patient underwent the experiment. Three different classifiers were employed in order to differentiate between the two cortical responses by means of electroencephalographic recordings. The offline analysis revealed that semantic classical conditioning can be applied successfully to enable basic communication using a non-muscular channel.

Original languageEnglish
Pages (from-to)267-274
Number of pages8
JournalBiological Psychology
Volume92
Issue number2
DOIs
Publication statusPublished - Feb 2013

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Keywords

  • Amyotrophic lateral sclerosis
  • Brain-computer interface
  • Electrical stimulation
  • Semantic conditioning

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology

Cite this

De Massari, D., Matuz, T., Furdea, A., Ruf, C. A., Halder, S., & Birbaumer, N. (2013). Brain-computer interface and semantic classical conditioning of communication in paralysis. Biological Psychology, 92(2), 267-274. https://doi.org/10.1016/j.biopsycho.2012.10.015