Brain concentrations of clobazam and N-desmethylclobazam and antileptazol activity

S. Caccia, G. Guiso, S. Garattini

Research output: Contribution to journalArticlepeer-review

Abstract

The results indicate that the antileptazol effect in mice is mediated by both clobazam and N-desmethylclobazam. Since the metabolite has a longer half-life than the parent compound, this probably explains why the antileptazol effect is longer in animal species in which N-desmethylclobazam is accumulated in significant amounts.

Original languageEnglish
Pages (from-to)295-296
Number of pages2
JournalJournal of Pharmacy and Pharmacology
Volume32
Issue number4
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Pharmaceutical Science
  • Pharmacology

Fingerprint Dive into the research topics of 'Brain concentrations of clobazam and N-desmethylclobazam and antileptazol activity'. Together they form a unique fingerprint.

Cite this