The results indicate that the antileptazol effect in mice is mediated by both clobazam and N-desmethylclobazam. Since the metabolite has a longer half-life than the parent compound, this probably explains why the antileptazol effect is longer in animal species in which N-desmethylclobazam is accumulated in significant amounts.
|Number of pages||2|
|Journal||Journal of Pharmacy and Pharmacology|
|Publication status||Published - 1980|
ASJC Scopus subject areas
- Pharmaceutical Science