Brain-core temperature of patients before and after orthotopic liver transplantation assessed by DWI thermometry

Gianvincenzo Sparacia, Roberto Cannella, Vincenzina Lo Re, Giuseppe Mamone, Koji Sakai, Kei Yamada, Roberto Miraglia

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To assess brain-core temperature of end-stage liver disease patients undergoing orthotopic liver transplantation (OLT) using a temperature measurement technique based on the apparent diffusion coefficient of the cerebrospinal fluid in the lateral ventricles. Materials and methods: The study group was composed of 19 patients with a model for end-stage liver disease (MELD) score of 23.7 who underwent MR imaging before and after OLT. MR imaging studies were performed with a 1.5T MR scanner. Brain-core temperature (T: °C) was calculated using the following equation from the apparent diffusion coefficient (D) of the cerebrospinal fluid in the lateral ventricles: (Formula presented.) measured with a DWI sequence (b value 1000 s/mm2). We compared brain-core temperature of all patients before and after OLT. Results: Brain-core temperature measurements were successfully taken in all patients before and after OLT. The measured brain-core temperature mean ± standard deviation was 38.67 ± 1.76 °C before OLT and 38.60 ± 0.99 °C after OLT, showing no significant difference (P = 0.643). Conclusions: Brain-core temperature was stable in patients undergoing OLT. DWI thermometry may provide a supplementary brain biomarker to confirm that cerebral blood flow and metabolism are stable in patients undergoing OLT.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalJapanese Journal of Radiology
DOIs
Publication statusAccepted/In press - Mar 19 2018

Keywords

  • Diffusion-weighted imaging temperature
  • DWI thermometry
  • MR imaging
  • Orthotopic liver transplantation
  • Ventricular temperatures

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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