Brain-derived neurotrophic factor: A new adipokine

Federica Sornelli, Marco Fiore, George N. Chaldakov, Luigi Aloe

Research output: Contribution to journalArticle

Abstract

Since leptin discovery in 1994, an extensive body of work has been demonstrating that adipose tissue (mainly its white phenotype) expresses not only metabolic, but also endocrine and paracrine phenotypes, particularly in adipobiology of disease. This new biology is achieved predominantly through secretion of adipokines, which include more than hundred highly active signaling proteins. However, studies on adipobiology of neurotrophins have recently emerged, nerve growth factor being one example of adipose-derived neurotrophins. Here we present data showing that brain-derived neurotrophic factor is also expressed in both white and brown adipose tissue.

Original languageEnglish
Pages (from-to)85-88
Number of pages4
JournalBiomedical Reviews
Volume18
Publication statusPublished - 2007

Keywords

  • Adipose tissue
  • Diabetes
  • Neurotrophins
  • Stress

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

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  • Cite this

    Sornelli, F., Fiore, M., Chaldakov, G. N., & Aloe, L. (2007). Brain-derived neurotrophic factor: A new adipokine. Biomedical Reviews, 18, 85-88.