Abstract
BACKGROUND AND PURPOSE - In migraine patients, functional imaging studies have shown changes in several brain gray matter (GM) regions. However, 1.5-T MRI has failed to detect any structural abnormality of these regions. We used a 3-T MRI scanner and voxel-based morphometry (VBM) to assess whether GM density abnormalities can be seen in patients with migraine with T2-visible abnormalities and to grade their extent. METHODS - In 16 migraine patients with T2-visible abnormalities and 15 matched controls, we acquired a T2-weighted and a high-resolution T1-weighted sequence. Lesion loads were measured on T2-weighted images. An optimized version of VBM analysis was used to assess regional differences in GM densities on T1-weighted scans of patients versus controls. Statistical parametric maps were thresholded at P
Original language | English |
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Pages (from-to) | 1765-1770 |
Number of pages | 6 |
Journal | Stroke |
Volume | 37 |
Issue number | 7 |
DOIs | |
Publication status | Published - Jul 2006 |
Keywords
- Magnetic resonance imaging
- Migraine
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Neuroscience(all)