Brain imaging and memory systems in humans: The contribution of PET methods

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The development of neuroimaging methods such as PET, has provided a new impulse to the study of the neural basis of cognitive functions, and has extended the field of inquiry from the analysis of the consequences of brain lesions to the functional investigations of brain activity, either in patients with selective neuropsychological deficits or in normal subjects engaged in cognitive tasks. Specific patterns of hypometabolism in neurological patients are associated with different profiles of memory deficits. [18F]FDG PET studies have confirmed the association of episodic memory with the structures of Papez's circuit and have shown correlations between short-term and semantic memory and the language areas. The identification of anatomo-functional networks involved in specific components of memory function in normal subjects is the aim of several PET activation studies. The results are in agreement with 'neural network' models of the neural basis of memory, as complex functions subserved by multiple interconnected cortical and subcortical structures.

Original languageEnglish
Pages (from-to)199-205
Number of pages7
JournalComptes Rendus de l'Academie des Sciences - Serie III
Volume321
Issue number2-3
DOIs
Publication statusPublished - Feb 1998

Fingerprint

Neuroimaging
brain
Brain
Imaging techniques
Data storage equipment
Neural Networks (Computer)
Episodic Memory
Fluorodeoxyglucose F18
Memory Disorders
Short-Term Memory
Semantics
Cognition
Language
lesion
Chemical activation
method
Association reactions
Neural networks
Networks (circuits)

Keywords

  • Activation
  • Amnesic patients
  • Memory
  • Positron emission tomography (PET)

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Ecology

Cite this

Brain imaging and memory systems in humans : The contribution of PET methods. / Perani, Daniela.

In: Comptes Rendus de l'Academie des Sciences - Serie III, Vol. 321, No. 2-3, 02.1998, p. 199-205.

Research output: Contribution to journalArticle

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