TY - JOUR
T1 - Brain metastases from solid tumors
T2 - Disease outcome according to type of treatment and therapeutic resources of the treating center
AU - Fabi, Alessandra
AU - Felici, Alessandra
AU - Metro, Giulio
AU - Mirri, Alessandra
AU - Bria, Emilio
AU - Telera, Stefano
AU - Moscetti, Luca
AU - Russillo, Michelangelo
AU - Lanzetta, Gaetano
AU - Mansueto, Giovanni
AU - Pace, Andrea
AU - Maschio, Marta
AU - Vidiri, Antonello
AU - Sperduti, Isabella
AU - Cognetti, Francesco
AU - Carapella, Carmine M.
PY - 2011
Y1 - 2011
N2 - Background: To evaluate the therapeutic strategies commonly employed in the clinic for the management of brain metastases (BMs) and to correlate disease outcome with type of treatment and therapeutic resources available at the treating center. Methods. Four Cancer centres participated to the survey. Data were collected through a questionnaire filled in by one physician for each centre. Results: Clinical data regarding 290 cancer patients with BMs from solid tumors were collected. Median age was 59 and 59% of patients had 3 brain metastases. A local approach (surgery and stereotactic radiosurgery) was adopted in 31% of patients. The local approach demonstrated to be superior in terms of survival compared to the regional/systemic approach (whole brain radiotherapy and chemotherapy, p =
AB - Background: To evaluate the therapeutic strategies commonly employed in the clinic for the management of brain metastases (BMs) and to correlate disease outcome with type of treatment and therapeutic resources available at the treating center. Methods. Four Cancer centres participated to the survey. Data were collected through a questionnaire filled in by one physician for each centre. Results: Clinical data regarding 290 cancer patients with BMs from solid tumors were collected. Median age was 59 and 59% of patients had 3 brain metastases. A local approach (surgery and stereotactic radiosurgery) was adopted in 31% of patients. The local approach demonstrated to be superior in terms of survival compared to the regional/systemic approach (whole brain radiotherapy and chemotherapy, p =
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U2 - 10.1186/1756-9966-30-10
DO - 10.1186/1756-9966-30-10
M3 - Article
C2 - 21244695
AN - SCOPUS:78651440131
VL - 30
JO - Journal of Experimental and Clinical Cancer Research
JF - Journal of Experimental and Clinical Cancer Research
SN - 0392-9078
IS - 1
M1 - 10
ER -