Brain neuraminidases and gangliosides.

G. Tettamanti, B. Venerando, B. Cestaro, A. Preti

Research output: Contribution to journalArticlepeer-review


A number of data of kinetics nature indicate that brain neuraminidases (the cytosol and the membrane bound enzyme) recognize the physical state of gangliosidic substrate, with immediate modification of the activity. The interactions between the enzyme(s) and the different physical forms of the substrate are still to be studied at the molecular level. The knowledge of these phenomena would greatly help understanding the role played by gangliosides in the neuronal plasma membrane.

Original languageEnglish
Pages (from-to)65-79
Number of pages15
JournalAdvances in Experimental Medicine and Biology
Publication statusPublished - 1976

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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