Brain SPECT imaging of ictal smile seizure

Sergio Modoni, Nicoletta Urbano, Marina Trivisano, Maria Grazia Pascarella, Giuseppe D'Orsi, Teresa Di Claudio, Luigi M. Specchio

Research output: Contribution to journalArticlepeer-review


Ictal smile is defined as a facial expression during a seizure, which usually translates happiness, clearly distinct from a tonic deviation of the mouth or other abnormal tonic-clonic movements involving the face, not associated to any happiness emotion (Epilepsia. 1998;39:1357-1360). It is a rare condition (6%-10% of patients; Epilepsia. 1998;39:1357-1360) and seems to be related to seizures arising from temporal or frontal regions (Brain. 2003;126:2121-2138).Anecdotal reports of brain perfusion SPECT performed during ictal and interictal phases (Epilepsia. 1998;39:1357-1360) do not supply, unfortunately, imaging documentation. Thus, we report the first evidence of brain perfusion abnormalities induced by ictal smile seizure.

Original languageEnglish
JournalClinical Nuclear Medicine
Publication statusAccepted/In press - Mar 11 2013

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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