Brain tuberculoma (Mycobacterium africanum): High index of suspicion helps in avoiding biopsy/surgery

A. Botturi, E. Prodi, A. Silvani, P. Gaviani, G. Vanoli, A. Carbone, A. Salmaggi

Research output: Contribution to journalArticlepeer-review


Partial seizures can be due to a growing cerebral lesion, which may be tumoral or inflammatory/infectious in nature. The differential diagnosis is obviously important; increasing immigration to Europe from Africa is leading to an increase of infectious disease involving also the central nervous system. The authors report imaging the a case of a brain tuberculoma due to Mycobacterium africanum mimicking brain tumor, in which diagnosis was possible by inoculum in guinea-pig of material obtained by mediastinal biopsy of enlarged lymph nodes. Specific treatment led to marked reduction in the size of the brain lesion.

Original languageEnglish
Pages (from-to)363-365
Number of pages3
JournalNeurological Sciences
Issue number2
Publication statusPublished - Apr 2012


  • Cerebral tuberculoma
  • Chest CT
  • Granulomatous epithelioidcell lymphadenitis
  • MRI
  • Mycobacterium africanum

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Dermatology


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