RADIOTERAPIA DEI TUMORI CEREBRALI NELL'INFANZIA

Translated title of the contribution: Brain tumor radiotherapy in childhood

V. Bernasconi, A. Bettinelli, L. Ceretti, M. Farabola, U. Vaccari, M. L. Zavanone

Research output: Contribution to journalArticle

Abstract

External radiotherapy with high energy photons in children's brain tumors improves the results of surgical treatment according to their histology. Radiotherapy treatment is a decisive factor in survival time and quality of life. Undifferentiated tumors with high radiosensitivity are treated when radiotherapy is the only means of treatment; in tumors presenting histologically low malignancy effective radiotherapy treatment is uncertain and the risk of radiotherapy damage is the predominant factor. Radiotherapists who treat children's brains which in many cases are not yet totally myelinized, must have good technical ability. The literature and personal experience show that in medulloblastomas irradiation of the entire central nervous system associated with chemotherapy gives a survival time of 5 years in 50% of the cases; in glioblastomas and anaplastic astrocytomas, fortunately rare in children, results are poor; in brainstem tumors the association of the extracranial shunt with radiotherapy has improved results of survival time at 5 years to 50%. A good quality of life is frequent and radiological effects are rare. It is clear that radiotherapy has reached its maximum. Progress is still to be made thanks to discoveries of more effective radiosensitizer or radioprotector compounds.

Original languageItalian
Pages (from-to)1433-1439
Number of pages7
JournalMinerva Medica
Volume75
Issue number24
Publication statusPublished - 1984

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Brain Neoplasms
Radiotherapy
High-Energy Radiotherapy
Quality of Life
Brain Stem Neoplasms
Neoplasms
Medulloblastoma
Radiation Tolerance
Astrocytoma
Therapeutics
Glioblastoma
Photons
Histology
Central Nervous System
Drug Therapy
Brain

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Bernasconi, V., Bettinelli, A., Ceretti, L., Farabola, M., Vaccari, U., & Zavanone, M. L. (1984). RADIOTERAPIA DEI TUMORI CEREBRALI NELL'INFANZIA. Minerva Medica, 75(24), 1433-1439.

RADIOTERAPIA DEI TUMORI CEREBRALI NELL'INFANZIA. / Bernasconi, V.; Bettinelli, A.; Ceretti, L.; Farabola, M.; Vaccari, U.; Zavanone, M. L.

In: Minerva Medica, Vol. 75, No. 24, 1984, p. 1433-1439.

Research output: Contribution to journalArticle

Bernasconi, V, Bettinelli, A, Ceretti, L, Farabola, M, Vaccari, U & Zavanone, ML 1984, 'RADIOTERAPIA DEI TUMORI CEREBRALI NELL'INFANZIA', Minerva Medica, vol. 75, no. 24, pp. 1433-1439.
Bernasconi V, Bettinelli A, Ceretti L, Farabola M, Vaccari U, Zavanone ML. RADIOTERAPIA DEI TUMORI CEREBRALI NELL'INFANZIA. Minerva Medica. 1984;75(24):1433-1439.
Bernasconi, V. ; Bettinelli, A. ; Ceretti, L. ; Farabola, M. ; Vaccari, U. ; Zavanone, M. L. / RADIOTERAPIA DEI TUMORI CEREBRALI NELL'INFANZIA. In: Minerva Medica. 1984 ; Vol. 75, No. 24. pp. 1433-1439.
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