Il trattamento dei tumori cerebrali in regime di ipofrazionamento accelerato della dose mediante tecniche cinetiche complanari non stereotassiche

Translated title of the contribution: Brain tumors and accelerated hypofractionation of the dose

R. Polico, A. Romeo, G. De Marco, N. D'Abbiero, T. Palmieri, C. Iotti, D. Ramundo

Research output: Contribution to journalArticle

Abstract

In Radiotherapy the Accelerated hypofractionation of the dose is less investigated than other fractionation schedules. However its application on small brain tumors and brain metastases, through stereotactic radiosurgery obtains in comparable oncological situations better results than conventional treatments. Accelerated hypofractionation also improves the efficiency of the radiotherapy departments. Since 1994 the clinical use on brain tumors of the Polycentric Multiple Arc technique started on. This technique allows us to reproduce dose distributions similar to those of the brachiterapy treatments with linear sources (inhomogeneous dose that increases inside the tumor and that quickly decreases outside the target) This technique allowed accelerated hypofractionated schedules also in the treatment of large and very large tumors. In this presentation we describe the possibility to reproduce and to ameliorate the main characteristics of the PMA technique using either IMRT or IMAT techniques through: a better conformation of the geometry of the dose distribution to the geometry of the target; a simplified control of the set-up of the treatment; a simplified planning of complex treatments (IP). Some examples of clinical application are discussed.

Original languageItalian
Pages (from-to)151-154
Number of pages4
JournalRivista Medica
Volume13
Issue number1
Publication statusPublished - Mar 2007

Fingerprint

Brain Neoplasms
Appointments and Schedules
Radiotherapy
Therapeutics
Radiosurgery
Neoplasms
Dose Hypofractionation
Neoplasm Metastasis
Brain

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Il trattamento dei tumori cerebrali in regime di ipofrazionamento accelerato della dose mediante tecniche cinetiche complanari non stereotassiche. / Polico, R.; Romeo, A.; De Marco, G.; D'Abbiero, N.; Palmieri, T.; Iotti, C.; Ramundo, D.

In: Rivista Medica, Vol. 13, No. 1, 03.2007, p. 151-154.

Research output: Contribution to journalArticle

@article{8c55ad99cd2c471f842d87f71187eb5a,
title = "Il trattamento dei tumori cerebrali in regime di ipofrazionamento accelerato della dose mediante tecniche cinetiche complanari non stereotassiche",
abstract = "In Radiotherapy the Accelerated hypofractionation of the dose is less investigated than other fractionation schedules. However its application on small brain tumors and brain metastases, through stereotactic radiosurgery obtains in comparable oncological situations better results than conventional treatments. Accelerated hypofractionation also improves the efficiency of the radiotherapy departments. Since 1994 the clinical use on brain tumors of the Polycentric Multiple Arc technique started on. This technique allows us to reproduce dose distributions similar to those of the brachiterapy treatments with linear sources (inhomogeneous dose that increases inside the tumor and that quickly decreases outside the target) This technique allowed accelerated hypofractionated schedules also in the treatment of large and very large tumors. In this presentation we describe the possibility to reproduce and to ameliorate the main characteristics of the PMA technique using either IMRT or IMAT techniques through: a better conformation of the geometry of the dose distribution to the geometry of the target; a simplified control of the set-up of the treatment; a simplified planning of complex treatments (IP). Some examples of clinical application are discussed.",
keywords = "Accelerated hypofractionation, Brain tumors, Radiotherapy",
author = "R. Polico and A. Romeo and {De Marco}, G. and N. D'Abbiero and T. Palmieri and C. Iotti and D. Ramundo",
year = "2007",
month = "3",
language = "Italian",
volume = "13",
pages = "151--154",
journal = "Rivista Medica",
issn = "1127-6339",
publisher = "New Magazine Edizioni S.r.l.",
number = "1",

}

TY - JOUR

T1 - Il trattamento dei tumori cerebrali in regime di ipofrazionamento accelerato della dose mediante tecniche cinetiche complanari non stereotassiche

AU - Polico, R.

AU - Romeo, A.

AU - De Marco, G.

AU - D'Abbiero, N.

AU - Palmieri, T.

AU - Iotti, C.

AU - Ramundo, D.

PY - 2007/3

Y1 - 2007/3

N2 - In Radiotherapy the Accelerated hypofractionation of the dose is less investigated than other fractionation schedules. However its application on small brain tumors and brain metastases, through stereotactic radiosurgery obtains in comparable oncological situations better results than conventional treatments. Accelerated hypofractionation also improves the efficiency of the radiotherapy departments. Since 1994 the clinical use on brain tumors of the Polycentric Multiple Arc technique started on. This technique allows us to reproduce dose distributions similar to those of the brachiterapy treatments with linear sources (inhomogeneous dose that increases inside the tumor and that quickly decreases outside the target) This technique allowed accelerated hypofractionated schedules also in the treatment of large and very large tumors. In this presentation we describe the possibility to reproduce and to ameliorate the main characteristics of the PMA technique using either IMRT or IMAT techniques through: a better conformation of the geometry of the dose distribution to the geometry of the target; a simplified control of the set-up of the treatment; a simplified planning of complex treatments (IP). Some examples of clinical application are discussed.

AB - In Radiotherapy the Accelerated hypofractionation of the dose is less investigated than other fractionation schedules. However its application on small brain tumors and brain metastases, through stereotactic radiosurgery obtains in comparable oncological situations better results than conventional treatments. Accelerated hypofractionation also improves the efficiency of the radiotherapy departments. Since 1994 the clinical use on brain tumors of the Polycentric Multiple Arc technique started on. This technique allows us to reproduce dose distributions similar to those of the brachiterapy treatments with linear sources (inhomogeneous dose that increases inside the tumor and that quickly decreases outside the target) This technique allowed accelerated hypofractionated schedules also in the treatment of large and very large tumors. In this presentation we describe the possibility to reproduce and to ameliorate the main characteristics of the PMA technique using either IMRT or IMAT techniques through: a better conformation of the geometry of the dose distribution to the geometry of the target; a simplified control of the set-up of the treatment; a simplified planning of complex treatments (IP). Some examples of clinical application are discussed.

KW - Accelerated hypofractionation

KW - Brain tumors

KW - Radiotherapy

UR - http://www.scopus.com/inward/record.url?scp=34248178590&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34248178590&partnerID=8YFLogxK

M3 - Articolo

AN - SCOPUS:34248178590

VL - 13

SP - 151

EP - 154

JO - Rivista Medica

JF - Rivista Medica

SN - 1127-6339

IS - 1

ER -