Brain volumetrics to investigate aging and the principal forms of degenerative cognitive decline: a brief review

Marco Bozzali; Mara Cercignani; Carlo Caltagirone

doi:10.1016/j.mri.2008.01.044

Brain volumetrics to investigate aging and the principal forms of degenerative cognitive decline: a brief review

Marco Bozzali, Mara Cercignani, Carlo Caltagirone

Fondazione Santa Lucia

Research output: Contribution to journal › Article

Abstract

The volume of the brain and of some of its structures can provide insight into the pathological process of several diseases. For this reason, in the recent years we saw a tremendous progress in the development of automated techniques for gaining information about global and regional atrophy. This paper reviews the main methods of analysis to quantify brain volume, and their application to the study of normal aging and the principal forms of degenerative dementias.

Original language	English
Pages (from-to)	1065-1070
Number of pages	6
Journal	Magnetic Resonance Imaging
Volume	26
Issue number	7
DOIs	https://doi.org/10.1016/j.mri.2008.01.044
Publication status	Published - Sep 2008

Keywords

Aging
Alzheimer's disease
Brain volumetrics
Dementia
Dementia with Lewy bodies
MRI
Parkinson disease

ASJC Scopus subject areas

Biophysics
Clinical Biochemistry
Structural Biology
Radiology Nuclear Medicine and imaging
Condensed Matter Physics

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Bozzali, M., Cercignani, M., & Caltagirone, C. (2008). Brain volumetrics to investigate aging and the principal forms of degenerative cognitive decline: a brief review. Magnetic Resonance Imaging, 26(7), 1065-1070. https://doi.org/10.1016/j.mri.2008.01.044

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