Brainstem encephalitis resulting from Epstein-Barr virus mimicking an infiltrating tumor in a child

Lucia Angelini, Marianna Bugiani, Federica Zibordi, Paola Cinque, Alberto Bizzi

Research output: Contribution to journalArticle

Abstract

A case of a child with subacute neurologic features and imaging findings consistent with a brainstem encephalitis that was discovered to be related to a primary central nervous system infection caused by Epstein-Barr virus is presented. A brainstem tumor was initially suspected, but a correct diagnosis was formulated on the basis of the favorable clinical course and the detection of positive Epstein-Barr virus serology. In contrast to a prompt recovery of neurologic signs the neuroimaging alterations persisted for a longer time. The present report emphasizes the possible role of Epstein-Barr virus in the pathogenesis of infectious neurologic disorders in childhood, underlining the unusual presentation of a brainstem encephalitis, and considers the discrepancy between the course of neurologic features and the evolution of imaging alterations. (C) 2000 by Elsevier Science Inc.

Original languageEnglish
Pages (from-to)130-132
Number of pages3
JournalPediatric Neurology
Volume22
Issue number2
DOIs
Publication statusPublished - Feb 2000

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Encephalitis
Human Herpesvirus 4
Brain Stem
Nervous System
Brain Stem Neoplasms
Central Nervous System Infections
Neoplasms
Serology
Neurologic Manifestations
Nervous System Diseases
Neuroimaging

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Neurology

Cite this

Brainstem encephalitis resulting from Epstein-Barr virus mimicking an infiltrating tumor in a child. / Angelini, Lucia; Bugiani, Marianna; Zibordi, Federica; Cinque, Paola; Bizzi, Alberto.

In: Pediatric Neurology, Vol. 22, No. 2, 02.2000, p. 130-132.

Research output: Contribution to journalArticle

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