Brainstem encephalitis resulting from Epstein-Barr virus mimicking an infiltrating tumor in a child

Lucia Angelini, Marianna Bugiani, Federica Zibordi, Paola Cinque, Alberto Bizzi

Research output: Contribution to journalArticle

Abstract

A case of a child with subacute neurologic features and imaging findings consistent with a brainstem encephalitis that was discovered to be related to a primary central nervous system infection caused by Epstein-Barr virus is presented. A brainstem tumor was initially suspected, but a correct diagnosis was formulated on the basis of the favorable clinical course and the detection of positive Epstein-Barr virus serology. In contrast to a prompt recovery of neurologic signs the neuroimaging alterations persisted for a longer time. The present report emphasizes the possible role of Epstein-Barr virus in the pathogenesis of infectious neurologic disorders in childhood, underlining the unusual presentation of a brainstem encephalitis, and considers the discrepancy between the course of neurologic features and the evolution of imaging alterations. (C) 2000 by Elsevier Science Inc.

Original languageEnglish
Pages (from-to)130-132
Number of pages3
JournalPediatric Neurology
Volume22
Issue number2
DOIs
Publication statusPublished - Feb 2000

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Neurology

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