GLIOMI TRONCO-ENCEFALICI IN ETA PEDIATRICA. DIAGNOSI, BILANCIO NEURORADIOLOGICO E FOLLOW-UP RM

Translated title of the contribution: Brainstem gliomas in pediatric age. Diagnosis, neuroradiological balance and Magnetic Resonance Imaging follow-up

C. Colosimo, M. Moschini, T. Tartaglione, A. Fileni, R. Riccardi, C. Di Rocco

Research output: Contribution to journalArticle

Abstract

Purpose of the study was to define the most common MRI features of pediatric brainstem gliomas at diagnosis and obtain objective neuroradiological staging that can be used to suggest prognosis and to quantitate the effects of treatment. Tectal gliomas were excluded from the present evaluation. MRI studies of 16 pediatric patients with proved brainstem glioma were retrospectively reviewed. The retrospective evaluation included MRI studies at diagnosis and during follow-up. Follow-up of the 16 patients ranged from 6 months to 4 years. MRI staging took in account for each tumor, site and origin, size, diffuse or focal growth, presence and degree of exophitic components, signal characteristics and hydrocephalus. All these data were correlated with histology and evolution of the lesions during the follow-up. Pons was involved in 14/16 patients, in most cases the tumor extended in one or more adjacent area (midbrain, medulla and even spinal cord or thalami). At diagnosis 9/16 gliomas showed significant exophitic components and hydrocephalus was observed only in 5 children. No clearcut correlations were found between signal modifications, enhancement after Gadolinium-DTPA and histology. In no cases treatment resulted in more than 50% reduction in size of the tumor. One patient developed CSF dissemination with secondary cranio-spinal deposits.

Translated title of the contributionBrainstem gliomas in pediatric age. Diagnosis, neuroradiological balance and Magnetic Resonance Imaging follow-up
Original languageItalian
Pages (from-to)327-329
Number of pages3
JournalRivista di Neuroradiologia
Volume7
Issue number2
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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    Colosimo, C., Moschini, M., Tartaglione, T., Fileni, A., Riccardi, R., & Di Rocco, C. (1994). GLIOMI TRONCO-ENCEFALICI IN ETA PEDIATRICA. DIAGNOSI, BILANCIO NEURORADIOLOGICO E FOLLOW-UP RM. Rivista di Neuroradiologia, 7(2), 327-329.